Results 91 to 100 of about 323,384 (318)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Relations between the Conference of African Labour Ministers and the Organization of African Unity: Report of the Administrative Secretary-General. [PDF]

open access: yes, 1974
Council of Ministers Twenty-Third Ordinary Session Mogadishu, June 1974.This report of the Administrative Secretary-General on the relationship between the conference of the African Labour Ministers and the Organizations of African Unity discussing the ...
Organization of African Unity
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Original Unity

open access: yesThe Linacre Quarterly, 2020
Thomas Merton’s vision of the original unity of humankind speaks of the oneness of the inner life of the Trinity. It is a vision that we need and one that the healers among us can offer us, whether they are acting as doctors or simply as Christians.
openaire   +3 more sources

Manchester Unity Building during Coronation week

open access: yes, 1937
Album 913 includes photographs of Manchester Unity Building, members, meetings, conferences and views of Sydney.
Photographer: Unknown   +1 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Unity Movement : principles and policy

open access: yes
A document in which the principles and policies of the Unity Movement are stated: non-collaboration, non-racialism, one nation, anti-imperialism, minimum demands, the working ...
Unity Movement
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Social isolation and loneliness among people living with experience of homelessness: a scoping review

open access: yesBMC Public Health
Social isolation and loneliness (SIL) are public health challenges that disproportionally affect individuals who experience structural and socio-economic exclusion.
James Lachaud   +7 more
doaj   +1 more source

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