Results 121 to 130 of about 1,861,870 (345)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Ecumenical Footprints in Nigeria: Pathways and Detours in Search of Christian Unity [PDF]
Michael Nnamdi Konye
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
ALBERT EINSTEIN: THE METHODOLOGICAL UNITY UNDERLYING SCIENCE AND RELIGION
, 1979 Roy D. Morrison
openalex +1 more source
ON THE NONRELATIVISTIC LIMIT OF LINEAR WAVE EQUATIONS FOR ZERO AND UNITY SPIN PARTICLES [PDF]
, 2008 P. Yu. Moshin, Jeferson Tomazelli
openalex +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
An algorithm for computing the Nth roots of unity in bit-reversed order
, 1980 Robert G. Keys
openalex +2 more sources
Unity, simplicity and balance: sustainable management of cultural historic environments of mountain summer farming [PDF]
, 2006 G. Swensen
openalex +1 more source
Cognizing Coexistence: Perceptions and their Synthetic Unity in Kant’s 3rd Analogy [PDF]
, 2023 Andrew Werner
openalex +1 more source