Results 241 to 250 of about 323,384 (318)

Implementing the screening for poverty and related social determinants and intervening to improve knowledge of and links to resources (SPARK) in primary care clinics across Canada. [PDF]

Fam Pract
Kosowan L, O'Rourke JJ, Howse D, Williams L, Adekoya I, Seshie AZ, Delahunty-Pike A, Smithman MA, Katz A, Abaga E, Zsager A, Cooney J, Robinson M, Senior DM, Aubrey-Bassler K, Marshall EG, Neudorf C, Muhajarine N, Fortuna I, Gupta A, Pinto AD.   +20 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Diverse platforms, diverse effects: Evidence from a 100-day study on social media and adolescent mental health. [PDF]

Curr Psychol
van der Wal A, Beyens I, Janssen LHC, Valkenburg PM.   +3 more
europepmc   +1 more source

!UNITY: A Theory of General UNITY

, 2002
Prasetya, I.S.W.B., Vos, T.E.J., Azurat, A., Swierstra, S.D.   +3 more
openaire   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

P555: Clinical utility returning of all types of medically relevant genomic sequencing findings: An observational study

Genetics in Medicine Open
Chloe Mighton, Rita Kodida, Salma Shickh, Marc Clausen, Emma Reble, Jordan Sam, Sonya Grewal, Seema Panchal, Melyssa Aronson, Susan Armel, Tracy Graham, Nicole Forster, Jose-Mario Capo-Chichi, Elena Greenfeld, Abdul Noor, Iris Cohn, Chantal Morel, Christine Elser, Andrea Eisen, June Carroll, Emily Glogowski, Kasmintan Schrader, Kelvin Chan, Kevin Thorpe, Jordan Lerner-Ellis, Raymond Kim, Yvonne Bombard   +26 more
doaj   +1 more source

The Influence of Religious Commitment on Social Cognition: An Exploratory Study of Social Representations of Peace Among a Sample of Graduates Cameroonians. [PDF]

Eur J Psychol
Etoundi JC, Goujon B, Gaymard S.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The integration of virtual reality and EEG: A step-by-step guideline. [PDF]

MethodsX
Krampe C, Wolfers J, Dean P.
europepmc   +1 more source