Results 51 to 60 of about 1,861,870 (345)

Brain Death as the End of a Human Organism as a Self-moving Whole [PDF]

open access: yes, 2021
The biophilosophic justification for the idea that “brain death” is death needs to support two claims: that what dies in human death is a human organism, not merely a psychological entity distinct from it; that total brain failure signifies the end of ...
Omelianchuk, Adam
core  

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Identifying homelessness using health administrative data in Ontario, Canada: how coding policies impact case validity

open access: yesInternational Journal of Population Data Science
Conducting longitudinal research about the health of people experiencing homelessness poses unique challenges. In Canada, we previously demonstrated that identification through health administrative databases permits population-level studies, despite ...
Lucie Richard   +4 more
doaj   +1 more source

The Unity of the Virtues in a Missionary Key [PDF]

open access: yes, 2018
The thesis of the unity of the virtues—one must possess all of the virtues to possess even one of them—was upheld in different forms by Plato, Aristotle, Augustine, and Aquinas.
Kim, Andrew J.
core   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Splenic artery aneurysm rupture in a pregnant woman with hepatosplenic schistosomiasis: case report and literature review

open access: yesEgyptian Liver Journal
Background Pregnancy is not uncommon in patients with non-cirrhotic portal hypertension. Rupture of a splenic artery aneurysm remains a rare complication, associated with a very poor maternal–fetal prognosis.
Chantelli Iamblaudiot Razafindrazoto   +9 more
doaj   +1 more source

Immune thrombocytopenic purpura

open access: yesJournal of Community Hospital Internal Medicine Perspectives, 2019
Immune thrombocytopenic purpura (ITP) is a bleeding disorder characterized by isolated thrombocytopenia (platelet count
Abir Zainal, Amr Salama, Richard Alweis
doaj   +1 more source

Pacemaker-Associated Post-cardiac Injury Syndrome Presenting with Tamponade and Recurrent Pleural Effusion

open access: yesClinical Medicine Insights: Case Reports, 2020
Post-cardiac injury syndrome (PCIS) is presumed to be an immune-mediated process. It affects the pericardium and, to a lesser extent, the epicardium, myocardium, and pleura.
Young Ju Lee   +6 more
doaj   +1 more source

Unitas and concordia in the confessions: significance for fellowship among Lutheran churches [PDF]

open access: yes, 1981
There is a sufficient basis in the Augsburg Confession for doctrinal and confessional unity among Lutherans. The paper suggests that while sufficient debate has taken place on the theological substance of the Confessions, not enough attention has been ...
Nostbakken, Roger W.
core   +1 more source

New Q matrices and their functional equations for the eight vertex model at elliptic roots of unity

open access: yes, 2008
The Q matrix invented by Baxter in 1972 to solve the eight vertex model at roots of unity exists for all values of N, the number of sites in the chain, but only for a subset of roots of unity. We show in this paper that a new Q matrix, which has recently
A.V. Razumov   +23 more
core   +1 more source

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