Results 111 to 120 of about 5,801 (304)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Poezja na wosku traconym w brązie 
– literackie, filozoficzne i muzyczne konteksty 
rzeźby Lidii Sztwiertni

open access: yesPostscriptum Polonistyczne, 2020
The theme of the article aims at interpreting the artistic creativity of Lidia Sztwiertnia – the sculptress from Bielsko­Biała – in the context of the philosophy of ‘multiplicity and unity of arts’.
Teresa Rączka
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Unity in Multiplicity: Towards Working Enterprise Systems

open access: yes, 2010
Enterprise systems are attractive exactly as they promise a stronger unity – integration, collaborationand standardization – across distinct and different organisational units of a business. However,empirical research on enterprise systems has documented
Gasparas, Jarulaitis, Monteiro, Eric
core  

UNITY IN MULTIPLICITY: ZEHRA ÇOBANLI’S "TULIPS

open access: yes, 2020
Türklerin gündelik yaşamında ve kültüründe tabiat ve çiçek sevgisi önemli bir yer tutmaktadır. Bu sevgi geçmişten günümüze farklı alanlardaki Türk sanat dallarına esin kaynağı olabilmektedir.
Kenan, L Mia
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Consensus Ecclesiae : Aquinas on the real and apparent unity of the Church [PDF]

open access: yes
Current sociological and theological observations point to the existence of a phenomenon known as «de-churching» in Western countries. Within the Church, there has been a long-standing discussion on the relativisation of some points of the doctrine and ...
Berry, John Anthony, Roszak, Piotr
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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