Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Colchicine and Major Adverse Cardiovascular Events in Patients With Established Coronary or Cerebrovascular Atherosclerotic Disease: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. [PDF]
Edris Ebrahim AA +7 more
europepmc +1 more source
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Initial Psychometric Evaluation of the Inventory of Parent and Peer Attachment in Greek Adolescents. [PDF]
Giannakopoulos G +3 more
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Interprofessional education at four joint medical and welfare universities: A comparison of face-to-face and distance learning. [PDF]
Nakamura S +9 more
europepmc +1 more source
Dynamic complexity of moral motivation: the roles of duty and self-interest. [PDF]
Kaplan U.
europepmc +1 more source
Mechanism of injury and fracture status influence outcomes after central cord injury. [PDF]
Pedro KM +10 more
europepmc +1 more source
Parameter Estimation of Microkinetic Models for Heterogeneous Catalysis. [PDF]
Ahmed MGT, Nath Roy B, Hasan MMF.
europepmc +1 more source

