Results 231 to 240 of about 5,636 (282)

Evaluation of Oral Doxycycline, Azithromycin, or Sequential Doxycycline-Azithromycin Treatment for Scrub Typhus. [PDF]

Mediterr J Hematol Infect Dis
Wang W, Dong Y, Liu H.
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Atezolizumab Plus Bevacizumab for Advanced Hepatocellular Carcinoma with Macroscopic Vascular Invasion: An Inverse Probability of Treatment Weighted Analysis. [PDF]

Cancers (Basel)
Kim J, Kim JH, Im BS, Kim GH, Chu HH, Gwon DI, Shin JH, Shim JH, Yoon SM, Kim S.   +9 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Home-Based Prehabilitation for Older Surgical Patients With Frailty: A Randomized Clinical Trial. [PDF]

JAMA Surg
McIsaac DI, Lee S, Fergusson D, Gillis C, Khadaroo RG, Meliambro A, Muscedere J, Eskander A, Moloo H, Nelson G, Saha T, Chun R, Serrano PE, Wijeysundera DN, Taljaard M, PREPARE Trial Investigator Group, Barnes K, Boet S, Boland L, Branje K, Breau R, Bryson GL, Dhalla I, Dixon E, Dobson G, Farnand M, Forster A, Gagne S, Hladkowicz E, Holroyd-Leduc J, Huang A, Hutton J, Jacobsohn E, Joanisse J, Johnson A, Johnson S, Khalil N, Kidd G, Lalu M, Lavallée LT, Le T, Levine M, Love C, McCartney C, McMullen M, Bergamascki LM, Moore R, Mozel M, Nagpal S, Nantel J, Power B, Scheede-Bergdahl C, Tamblyn-Watts L, Thavorn K, Trottier D, van Walraven C, Yang I.   +56 more
europepmc   +1 more source

Input to the European strategy for particle physics: strong-field quantum electrodynamics. [PDF]

Eur Phys J Plus
Sarri G, King B, Blackburn T, Ilderton A, Boogert S, Bulanov SS, Bulanov SV, Di Piazza A, Ji L, Karbstein F, Keitel CH, Krajewska K, Malka V, Mangles SPD, Mathieu F, McKenna P, Meuren S, Mirzaie M, Ridgers C, Seipt D, Thomas AGR, Uggerhøj U, Vranic M, Wing M.   +23 more
europepmc   +1 more source

Queer-religious symbol analysis (QRSA): A semiotic method for reframing Hindu iconography. [PDF]

MethodsX
Ac PS, Gk C.
europepmc   +1 more source

Cracks in the pattern: Gallagher's theory of the self and the dynamics of schizophrenic selfhood. [PDF]

Front Psychiatry
Fazakas I, Fuchs T, Thoma S, Bois C, Gozé T.   +4 more
europepmc   +1 more source

Prophylaxis for venous thromboembolism in traumatic brain injury: protocol for a randomised controlled trial. [PDF]

BMJ Open
Pirouzmand F, Mathieu F, Mansouri A, Kavikondala K, Alkins R, Boyd JG, Christie S, Couillard P, Cusimano MD, Engels PT, English S, Fourney D, Fowler R, Geerts W, Gooderham PA, Griesdale D, Hunter G, Jabehdar Maralani P, Kelly ME, Klein G, Kramer AH, Kromm J, Kutsogiannis DJ, Lauzier F, Machnowska M, Maslove DM, Mejia-Mantilla J, Midha R, Misra B, Murphy L, O'Kelly CJ, Patel C, Pinto RL, Pronovost AP, Sekhon M, Sharma SV, Sinclair J, Tsai E, Turgeon AF, Warade A, Scales DC, PROTEST investigators.   +41 more
europepmc   +1 more source