Electroencephalographic signal dimension provides the necessary stability of measurements for the unbiased evaluation of antiseizure medications, unlike seizure frequency: Overcoming drawbacks of seizure occurrence variability. [PDF]
EpilepsiaRizzi M +4 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Valley-Dependent Topological Interface States in Biased Armchair Nanoribbons of Gapless Single-Layer Graphene for Transport Applications. [PDF]
Materials (Basel)Huang ZH, Lai JY, Wu YS.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Self-learning virtual organisms in a physics simulator: on the optimal resolution of their visual system, the architecture of the nervous system and the computational complexity of the problem. [PDF]
Vavilovskii Zhurnal Genet SelektsiiZenin MS, Devyaterikov AP, Palyanov AY.
europepmc +1 more source
A Criterion for the Existence of the Twosided Unity Element of Semigroups
Proceedings of the Japan Academy, 1971 openaire +4 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Information thinking: the transformation of complexity and scientific thinking. [PDF]
Front PsycholWu T, Zhang H, Wu K.
europepmc +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source