Results 11 to 20 of about 980,845 (193)

In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIbα

Scientific Reports, 2021
The interaction of platelet GPIbα with von Willebrand factor (VWF) is essential to initiate platelet adhesion and thrombosis, particularly under high shear stress conditions. However, no drug targeting GPIbα has been developed for clinical practice. Here
Benjamin Xiaoyi Li, Xiangrong Dai, Xiaohong Ruby Xu, Reheman Adili, Miguel Antonio Dias Neves, Xi Lei, Chuanbin Shen, Guangheng Zhu, Yiming Wang, Hui Zhou, Yan Hou, Tiffany Ni, Yfke Pasman, Zhongqiang Yang, Fang Qian, Yanan Zhao, Yongxiang Gao, Jing Liu, Maikun Teng, Alexandra H. Marshall, Eric G. Cerenzia, Mandy Lokyee Li, Heyu Ni   +22 more
doaj   +1 more source

Associations of resilience with quality of life levels in adults experiencing homelessness and mental illness: a longitudinal study

Health and Quality of Life Outcomes, 2021
Background Homelessness constitutes a traumatic period that adversely impacts health and quality of life outcomes. The potential mitigating effects of resilience on quality of life levels in people experiencing homelessness are underresearched.
Cilia Mejia-Lancheros, Julia Woodhall-Melnik, Ri Wang, Stephen W. Hwang, Vicky Stergiopoulos, Anna Durbin   +5 more
doaj   +1 more source

DJ-1 Deficiency Protects against Sepsis-Induced Myocardial Depression

Antioxidants, 2023
Oxidative stress is considered one of the early underlying contributors of sepsis-induced myocardial depression. DJ-1, also known as PARK7, has a well-established role as an antioxidant.
James N. Tsoporis, Hajera Amatullah, Sahil Gupta, Shehla Izhar, Amin M. Ektesabi, Chirag M. Vaswani, Jean-Francois Desjardins, Golam Kabir, Ana Paula Teixera Monteiro, Amir K. Varkouhi, Nikolaos Kavantzas, Vasileios Salpeas, Ioannis Rizos, John C. Marshall, Thomas G. Parker, Howard Leong-Poi, Claudia C. dos Santos   +16 more
doaj   +1 more source

Embedding rapid reviews in health policy and systems decision-making: Impacts and lessons learned from four low- and middle-income countries

Health Research Policy and Systems, 2023
Background Demand for rapid evidence-based syntheses to inform health policy and systems decision-making has increased worldwide, including in low- and middle-income countries (LMICs).
Reid C. Robson, Sonia M. Thomas, Étienne V. Langlois, Rhona Mijumbi, Ismael Kawooya, Jesmin Antony, Melissa Courvoisier, Krystle Amog, Robert Marten, Ivdity Chikovani, Devaki Nambiar, Rajani R. Ved, Soumyadeep Bhaumik, Nur Zahirah Balqis-Ali, Sondi Sararaks, Shakirah Md. Sharif, Rugare Abigail Kangwende, Ronald Munatsi, Sharon E. Straus, Andrea C. Tricco   +19 more
doaj   +1 more source

Ultrabright narrow-band telecom two-photon source for long-distance quantum communication [PDF]

, 2018
We demonstrate an ultrabright narrow-band two-photon source at the 1.5 -\mu m telecom wavelength for long-distance quantum communication. By utilizing a bow-tie cavity, we obtain a cavity enhancement factor of $4.06\times 10^4$.
20361199, Horikiri, Tomoyuki, Ikeda, Kohei, Inoue, Shuichiro, Kosaka, Hideo, Namekata, Naoto, Niizeki, Kazuya, Okamura, Kotaro, Takei, Nobuyuki, Xie, Xiuping, Zheng, Mingyang   +10 more
core   +2 more sources

Comparative Study of Chemosensory Dysfunction in COVID-19 in 2 Geographically Distinct Regions

Ear, Nose & Throat Journal, 2023
Objective: To directly compare the prevalence of chemosensory dysfunction (smell and taste) in geographically distinct regions with the same questionnaires.
Daniel J. Lee MD, Daniella Daliyot RN, MSc, Ri Wang MMath, Joel Lockwood MD, Paul Das MD, MSc, Eyal Zimlichman MD, MSc, John M. Lee MD, MSc   +6 more
doaj   +1 more source

Achilles And The Tortoise: Some Caveats To Mathematical Modeling In Biology [PDF]

, 2018
Mathematical modeling has recently become a much-lauded enterprise, and many funding agencies seek to prioritize this endeavor. However, there are certain dangers associated with mathematical modeling, and knowledge of these pitfalls should also be part ...
Gilbert, Scott F.
core   +3 more sources

Developing the intersectionality supplemented Consolidated Framework for Implementation Research (CFIR) and tools for intersectionality considerations

BMC Medical Research Methodology, 2023
Background The concept of intersectionality proposes that demographic and social constructs intersect with larger social structures of oppression and privilege to shape experiences.
Isabel B. Rodrigues, Christine Fahim, Yasmin Garad, Justin Presseau, Alison M. Hoens, Jessica Braimoh, Diane Duncan, Lora Bruyn-Martin, Sharon E. Straus   +8 more
doaj   +1 more source

What is it like to have a body? [PDF]

, 2012
Few questions in psychology are as fundamental or as elusive as the sense of one’s own body. Despite widespread recognition of the link between body and self, psychology has only recently developed methods for the scientific study of bodily awareness ...
Haggard, P., Longo, Matthew R.
core   +1 more source

A rational approach on the use of extracorporeal membrane oxygenation in severe hypoxemia: advanced technology is not a panacea

Annals of Intensive Care, 2021
Veno-venous extracorporeal membrane oxygenation (ECMO) is a helpful intervention in patients with severe refractory hypoxemia either because mechanical ventilation cannot ensure adequate oxygenation or because lung protective ventilation is not feasible.
Evangelia Akoumianaki, Annemijn Jonkman, Michael C. Sklar, Dimitris Georgopoulos, Laurent Brochard   +4 more
doaj   +1 more source