Results 171 to 180 of about 5,502,919 (295)
Trends and Future Directions in Organic Chemistry for Drug Discovery
Organic synthesis is being reshaped by the convergence of catalytic innovation, automation, artificial intelligence, and emerging therapeutic modalities. Late‐stage functionalization, photoredox and electrochemical methods, biocatalysis, flow chemistry, DELs, and proximity‐based drugs are examined as components of closed‐loop discovery.
Paweł Kozyra, Maciej Masłyk
wiley +1 more source
A Half-Century of Supramolecular Thermodynamics: A Retrospective of Our Multidisciplinary Approach. [PDF]
Danil de Namor AF, Al Hakawati N.
europepmc +1 more source
Alkali Metal Mediated Redox Tuning in Bis(μ‐OH) Dinickel(II) Complexes
Alkali metal ions are ubiquitous in both enzymatic and synthetic catalytic media. The present study highlights the powerful influence common monocations have on the structural and electrochemical properties of catalytically relevant bis(μ‐hydroxo) dinickel diamond cores, through a well‐defined series of heterometallic clusters (Li+, Na+, K+, and Cs ...
Matthew L. Peris, Joshua A. Buss
wiley +1 more source
NUP1/NUP136 is essential for obligatory crossover formation during meiosis in Arabidopsis. [PDF]
Fernández-Jiménez N +4 more
europepmc +1 more source
Two previously uncharacterized heterocyclic imines, 3‐iminooxetane and 3‐oxazoline, are generated simultaneously by irradiation of 3‐azidooxetane under matrix isolation conditions. The infrared spectra provide reference data for future gas‐phase studies and may facilitate their search in the interstellar medium.
Mika Maehara +4 more
wiley +1 more source
Germline-Restricted Chromosome (GRC) in Diploid and Polyploid Spermatocytes of the Eurasian Bullfinch, <i>Pyrrhula pyrrhula</i> (Fringillidae, Passeriformes, Aves). [PDF]
Grishko E +3 more
europepmc +1 more source
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius +6 more
wiley +1 more source
A male-transmitted B chromosome undergoes strong meiotic drag in females of the jewel wasp Nasonia vitripennis. [PDF]
Ferree PM +4 more
europepmc +1 more source
A Fast and Highly Stable Aqueous Calcium‐Ion Battery for Sustainable Energy Storage
Aqueous batteries provide a low‐cost, safer alternative to lithium‐ion batteries, but their viability is often limited by rapid electrode degradation. This study shows that replacing K+ with divalent Ca2+ ions in the electrolyte significantly boosts the stability of both copper hexacyanoferrate cathodes and polyimide anodes, enabling fast‐charging ...
Raphael L. Streng +4 more
wiley +1 more source

