Results 171 to 180 of about 3,084,757 (296)

Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray

open access: yesChemFoodChem, EarlyView.
This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi   +2 more
wiley   +1 more source

Modulation of Epigenetic Control by Advanced Molecular Tweezers

open access: yesChemistry – A European Journal, EarlyView.
Tailored dimeric molecular tweezers recognize the DNA‐binding part of Histone H4 and interrupt the essential histone‐DNA interaction. ABSTRACT This work addresses the question if supramolecular systems can be tailored to interfere with posttranslational modifications (PTM) and epigenetics.
My‐Hue‐Le   +9 more
wiley   +1 more source

Controlling Structures and Properties of NaCl‐Containing Alginate/Polyacrylamide Tough Hydrogels via a One‐Pot Process

open access: yesChemistry – A European Journal, EarlyView.
NaCl‐incorporated alginate/polyacrylamide tough hydrogels are prepared through a facile one‐pot strategy that enables direct ion incorporation during network formation. Compared with conventional soaking, this approach reduces diffusion‐limited ion gradients and provides a more spatially consistent ion distribution.
Taeuk Eom   +6 more
wiley   +1 more source

Two‐Coordinate 13‐Electron PdI Complexes Stabilized by the Bulky DIMeIHeptCl NHC Ligand

open access: yesChemistry – A European Journal, EarlyView.
Bulky N‐heterocyclic carbene (NHC) ligand DiMeIHeptCl stabilizes rare two‐coordinate 13‐electron PdI species. These monomeric complexes are directly observed crystallographically and by electron paramagnetic resonance (EPR) spectroscopy, and display unusual structures and radical‐type reactivity, forming Pd0(NHC) via Pd─X bond homolysis or ...
Volodymyr Semeniuchenko   +8 more
wiley   +1 more source

Trends and Future Directions in Organic Chemistry for Drug Discovery

open access: yesChemistry – A European Journal, EarlyView.
Organic synthesis is being reshaped by the convergence of catalytic innovation, automation, artificial intelligence, and emerging therapeutic modalities. Late‐stage functionalization, photoredox and electrochemical methods, biocatalysis, flow chemistry, DELs, and proximity‐based drugs are examined as components of closed‐loop discovery.
Paweł Kozyra, Maciej Masłyk
wiley   +1 more source

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