Results 31 to 40 of about 11,579,260 (289)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Usability analysis of advertising websites interfaces with the use of the universal design principles

open access: yesJournal of Computer Sciences Institute, 2023
The aim of the research was to observe how the usage of the universal design principles influences on the accessibility and usability of websites. As one of the analysis’ subjects there was chosen the popular advertising website.
Jan Marciniec, Dominik Kondraciuk
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A culture of universal empathy in design at the south east technological university carlow.

open access: yes, 2015
This paper discusses the development of a culture of ‘Universal Empathy’ within Product Design programmes at the Institute of Technology Carlow. The concept draws from the inclusive, holistic nature of Universal Design and its principles together with ...
White, P.J., Dempsey, Hilary
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

A proposal of an evaluation model under the principles of universal design [PDF]

open access: yes, 2010
The aim of this work is to try to set out how the Universal Design (UD) paradigm can influence the process of product design and how the models of evaluation should work for products designed for all users. Firstly, we will give a short introduction of
Gual, Jaume   +3 more
core   +1 more source

A flipped classroom model for inquiry-based learning in primary education context

open access: yesResearch in Learning Technology, 2020
A multi-case study will be presented in this publication which aimed to address an important gap in the current literature concerning the effective implementation of a flipped classroom (FC) model in a particular educational setting.
Maria Loizou, Kyungmee Lee
doaj   +1 more source

Revisiting the English Textbook Accessibility based on the Universal Design Learning Principles

open access: yesIndonesian Journal of Disability Studies, 2022
Textbooks based on the teaching and learning process should be relevant to any students including students with disability, there are a lot of textbooks that are not suitable enough to provide accessible material.
Emeraldine Asanantha   +1 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

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