Results 41 to 50 of about 83,468 (276)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Exhibition activity as a tool to promote the industrial enterprise [PDF]

, 2019
The article suggests the approach to manage exhibition activity at the industrial enterprise, works out the sequence and essence of the management procedures, and their information provision. According to the author’s approach, the exhibition activity of
Illiashenko, Nataliia, Illiashenko, Sergii, Merkun, Iryna   +2 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

The Micro-history of a world event: intention, perception and imagination at the Exposition universelle de 1867

Museum & Society, 2008
Universal exhibitions are almost exclusively described as representations of an outside reality. The authenticity of the exhibits and the relation between the display and the real thing are put into consideration to investigate the political aims and ...
Volker Barth
doaj  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

WORLD’S FAIRS IN THE SERVICE OF NATIONAL BRANDING – THE STATE OF RESEARCH, KEY ELEMENTS OF EXHIBITORS’ PRESENTATIONS, EXEMPLIFICATION OF IMAGE-BUILDING ACTIVITIES

Modern Management Review, 2022
World’s fairs (Expos) are nowadays perceived as so-called mega events, which are attended mainly to build a desired image of exhibiting countries. The article aimed at exploring literature to determine the extent to which the concept in question has been
Marcin Gębarowski
doaj   +1 more source

‘Engage the World’: examining conflicts of engagement in public museums [PDF]

, 2014
Public engagement has become a central theme in the mission statements of many cultural institutions, and in scholarly research into museums and heritage.
Ashley S., Baeker G., Black G., Brown A., Butler S.R., Cameron F., CJPME, Clifford J., Cornwall A., Ellison J., Fraser N., Grenoways H., Grinell K., Halbert D.J., Janes R., Luke T.W., McLean F., Message K., Mouffe C., Rentschler R., Royal Ontario Museum, Sandell R., Simon N., Smith L., Smith L., Susan L.T. Ashley, Tkacz N.   +26 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

¿Geopolíticas de mundos efímeros?

Terra Brasilis, 2018
The changes in the spatial organization of the World Fairs expressed the general vicissitudes of the global economy, the geopolitical tensions and the cultural values of their time in a miniaturized world created as a spectacle for a growing public ...
Carla Lois
doaj   +1 more source

Decolonising the museum?

Culture Unbound: Journal of Current Cultural Research, 2022
As institutions that arose during the European age of imperial expansion to glorify and display the achievements of empire, museums have historically been deeply implicated in the colonial enterprise.
Vanessa Whittington
doaj   +1 more source