Results 41 to 50 of about 53,530 (277)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Energy-efficient multi-cell resource allocation in cognitive radio-enabled 5G systems

EURASIP Journal on Advances in Signal Processing, 2019
In this paper, we propose an energy-efficient resource allocation (RA) algorithm in cognitive radio-enabled 5th generation (5G) systems, where the scenario including one primary system and multiple secondary cells is considered.
Hengwei Lv, Pandong Li, Qinmengying Yan, Haijian Zhang   +3 more
doaj   +1 more source

A Multi-Carrier Waveform Design for 5G and beyond Communication Systems

Mathematics, 2020
The next generation communication network (NGCN) is expected to provide higher spectral efficiency, low latency, large throughput and massive machine-to-machine type communications. In this regard, the design of the multi-carrier waveform (MCW) is posing
Imran Baig, Umer Farooq, Najam Ul Hasan, Manaf Zghaibeh, Varun Jeoti   +4 more
doaj   +1 more source

Implicit Kripke Semantics and Ultraproducts in Stratified Institutions

, 2016
We propose stratified institutions (a decade old generalised version of the theory of institutions of Goguen and Burstall) as a fully abstract model theoretic approach to modal logic.
Diaconescu, Răzvan
core   +1 more source

Waveform Design for 5G and Beyond [PDF]

, 2018
5G is envisioned to improve major key performance indicators (KPIs), such as peak data rate, spectral efficiency, power consumption, complexity, connection density, latency, and mobility.
Arslan, H., Demir, Ali Fatih, Elkourdi, M., Ibrahim, M.   +3 more
core   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Observation of the intrinsic magnetic susceptibility of highly purified single-wall carbon nanotubes

, 2015
We report the observation of the intrinsic magnetic susceptibility of highly purified SWCNT samples prepared by a combination of acid treatment and density gradient ultracentrifugation (DGU).
Hata, Kenji, Maniwa, Yutaka, Miyata, Yasumitsu, Nakai, Yusuke, Saito, Takeshi, Tsukada, Ryo   +5 more
core   +1 more source

Design and Implementation of Adaptive Universal Filtered Multi Carrier for 5G and Beyond

International Journal of Computer Network and Information Security, 2022
The current generation (5G) mobile communication system promises to accommodate a wide range of new applications and use scenarios, resulting in more flexible and unified connection. To satisfy the required criteria, the current waveform was replaced with new UF-OFDM, which combines the advantages of OFDM with enhanced spectral characteristics and ...
Mohammed H. Ali, Noora H. Sherif
openaire   +1 more source

Micropatterned Biphasic Printed Electrodes for High‐Fidelity on‐Skin Bioelectronics

Advanced Functional Materials, EarlyView.
Micropatterned biphasic printed electrodes achieve unprecedented skin conformity and low impedance by combining liquid‐metal droplets with microstructured 3D lattices. This scalable approach enables high‐fidelity detection of ECG, EMG, and EEG signals, including alpha rhythms from the forehead, with long‐term comfort and stability.
Manuel Reis Carneiro, Telmo Lopes, André F. Silva, Carmel Majidi, Mahmoud Tavakoli   +4 more
wiley   +1 more source