Results 31 to 40 of about 245,016 (254)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

El libro primero de la Historia romana de Veleyo Patérculo: caracterización y contenido

open access: yesErga-Logoi, 2019
The analysis of the conserved section of the first book of Velleius’ Roman History allows the reinterpretation of its alleged universal nature. Its so-alled universal contents can be reinterpreted as an excursus in order to introduce the complex ...
Miguel Angel Rodriguez Horrillo
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Metaphors of memory: Count Kokovtsov and his “Fragments of memories”

open access: yesLittera Scripta, 2016
This article is devoted to the reconstruction of “Fragments of memories of my childhood and the time in the Lyceum”, the memoirs of Count Vladimir Nikolayevich Kokovtsov, the former Minister of Finance and Chairman of the Council of Ministers of the ...
Mikhail Kovalev
doaj  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Osmanlı Devleti’nde 1704 Yılı Sikke Tashihi ve Fiyatlara Etkisi

open access: yesJournal of Universal History Studies, 2021
Osmanlı klasik döneminde madeni para rejimi hâkim olduğundan piyasada kırkık, vezni ve ayarı düşük paralar çoğalınca fiyatlar yükselir, alım gücü azalırdı.
Sevda Danık
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Kuman- Kıpçaklarla Rusların Siyasi İlişkileri (1055-1120)

open access: yesJournal of Universal History Studies, 2020
Dünya tarihinde büyük tesirler bırakan Türk kavimleri veya devletleri, anayurtları Orta Asya coğrafyasından; iklim yetersizliği, otlak alanlarının daralması, çeşitli hastalıkların meydana gelmesi ve bir takım siyasi nedenlerden dolayı batıya doğru göç ...
Hasan Ceyhan
doaj   +1 more source

Arşag Alboyacıyan’ın Kayseri Ermenileri Tarihi Kitabına Göre Kayseri Nüfusu

open access: yesJournal of Universal History Studies, 2022
Arşag Alboyacıyan, 1937 yılında Kahire’de iki cilt olarak yayınlanmış olan “Kayseri Ermenileri Tarihi” adlı kitabının ilk cildinin üçüncü bölümü içerisinde 692-700 sayfaları arasında yer alan “Ahali ve Ermeni Nüfusu” başlığı altında Kayseri’nin hem genel
Haşim Erdoğan, Batuhan Yüksel
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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