Results 41 to 50 of about 245,016 (254)

Persian Medicine Standard Terminology

Traditional and Integrative Medicine
Persian Medicine (PM) is an ancient and holistic healthcare approach that has been practiced for thousands of years. While PM is often considered to be a traditional or alternative form of medicine, it has a rich history and a wealth of knowledge that ...
Babak Daneshfard, Shahrzad Irannejad, Mohammad Shams, Meysam Shirzad, Mahdi Alizadeh Vaghasloo, Alireza Abbasian, Ayeh Naghizadeh, Morteza Mojahedi   +7 more
doaj   +1 more source

A Tentative Review of the Studies on the Environmental History of Ancient China

Contemporary Social Sciences, 2017
The existing research findings of our environmental history fail to attach due importance to the environmental history of ancient China. The studies of China’s environmental history should extend the time scope further to more ancient times and raise ...
Zhao Jiuzhou
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Adnan Menderes’in Siyasal Karakteri ve 27 Mayıs

Journal of Universal History Studies, 2020
Türk Siyasi Tarihi, 1945’te demokrasi adına önemli bir döneme girerek çok partili hayata geçmiş; dört yıl sonra da demokrasi daha da sağlamlaşmıştır. 1950 Genel Seçimleri iktidar ve muhalefette yer değişikliğine yol açmıştır. Cumhuriyet Halk Partisi’nden
Selma Göktürk Çetinkaya
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Les Portraits nationaux à l’Exposition universelle parisienne de 1878 : un projet de galerie historique

Bulletin du Centre de Recherche du Château de Versailles
The Universal Exhibition held in Paris in 1878 included, among numerous events, one of a special kind, which can be described as the first attempt in France to conceive a thematic temporary exhibition of ancient art, based on prior research and a well ...
Stéphane Paccoud
doaj   +1 more source

Cunoaştere şi adevăr la Vasile Conta. Semnificații pentru teoria istoriei

Studii de Istorie a Filosofiei Româneşti, 2021
The theory of knowledge of the philosopher of universal undulation, in which experience has a leading role, distinguishes between two broad categories of forms of knowledge: the elementary ones – sensations or perceptions – and the abstract ideas.
Mihai Popa
doaj  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source