Results 71 to 80 of about 2,131,657 (304)
Revista Panamericana de Salud Pública, 2020 El desafío de avanzar hacia la materialización del derecho a la salud para todos a través de la estrategia para el acceso y la cobertura universal de salud (salud universal) requiere de múltiples condiciones y acciones.
Osvaldo Artaza +7 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Household behavior change for climate change response: an integral scan [PDF]
, 2009 The question of how to successfully facilitate the changes needed to avoid dangerous climate change has become a critical one for researchers and practitioners.
Riedy, C
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Revista Histedbr On-line, 2015 As discussões recentes sobre o tema da educação integral em tempo integral no campo da educação apresentam a predominância da perspectiva do programa Mais Educação que é uma estratégia do Ministério da Educação visando a ampliação da jornada escolar nas ...
Bruno Adriano Rodrigues da Silva
doaj +1 more source
Baltic Journal of Sport and Health Sciences, 2020 Background. Basketball coaches need to find or create an effective training program while developing and training mini-basketball players. Only an effective and certified training program can help optimize the training process and bring success.
Kęstutis Matulaitis +4 more
doaj +1 more source
On universally integrable functions [PDF]
Proceedings of the American Mathematical Society, 1955 Let X be an abstract space and 21 be a Boolean algebra of sets E in X. Let p be a finite collection of disjoint sets { Ek } in W which partition X. The partitions p form a lattice [1 ] if we define p
openaire +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source