Results 181 to 190 of about 122,810 (295)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Two Dynamical Scenarios for Binned Master Sample Interpretation. [PDF]

Entropy (Basel)
Montani G, Fazzari E, Carlevaro N, Dainotti MG.   +3 more
europepmc   +1 more source

IceCube-Gen2: The window to the extreme Universe

, 2021
M. G. Aartsen, Rasha Abbasi, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, Cyril Martin Alispach, P. Allison, N. M. Amin, K. Andeen, T. Anderson, I. Ansseau, G. Anton, C. Argüelles, T. C. Arlen, J. Auffenberg, Spencer Axani, H. Bagherpour, X. Bai, Aswathi Balagopal, Anastasia Maria Barbano, I. Bartos, Benjamin Bastian, Vedant Basu, V. Baum, S. Baur, R. Bay, J. J. Beatty, K-H Becker, J. Becker Tjus, S. BenZvi, D. Berley, E. Bernardini, Dominique Besson, G. Binder, D. Bindig, E. Blaufuss, Summer Blot, C. Böhm, M. Böhmer, S. Böser, O. Botner, J. Böttcher, Etienne Bourbeau, J. Bourbeau, Federica Bradascio, J. Braun, S. Bron, Jannes Brostean-Kaiser, A. Burgman, Ryan T. Burley, J. Büscher, Raffaela Busse, Mauricio Bustamante, Michael Campana, Erin Carnie-Bronca, T. Carver, C Chen, Pisin Chen, E. Cheung, D. Chirkin, S. Choi, Brian Clark, K. Clark, Lew Classen, Alan Coleman, G. H. Collin, A. Connolly, J. M. Conrad, Paul Coppin, Pablo Correa, Doug Cowen, R. Cross, Pranav Dave, Cosmin Deaconu, C. De Clercq, James DeLaunay, Simon De Kockere, H.-P. Dembinski, Kunal Deoskar, S. De Ridder, Abhishek Desai, P. Desiati, K. D. de Vries, G. de Wasseige, M de With, T. DeYoung, Sukeerthi Dharani, A. Diaz, J. C. Díaz–Vélez, Hrvoje Dujmović, M. Dunkman, M. A. DuVernois, Emily Dvorak, Thomas Ehrhardt, P. Eller, R. Engel, John Evans, P. A. Evenson   +99 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Arrow of Time in Quantum Mechanics and Set Theory. [PDF]

Entropy (Basel)
Król J.
europepmc   +1 more source

The universe in a classroom [PDF]

, 2018
Jeffrey Maloy
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Exploring the protein universe with distant similarity detection methods. [PDF]

Protein Sci
Sahakyan H, Mutz P, Tobiasson V, Koonin EV.   +3 more
europepmc   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

An advanced multi-attribute decision-making model for Urban transportation planning based on complex intuitionistic fuzzy sets with hierarchical parameters. [PDF]

Sci Rep
Alballa T, Asghar A, Alharbi T, Shahzadi I, Abd El-Wahed Khalifa H.   +4 more
europepmc   +1 more source