Results 11 to 20 of about 10,055 (179)
Control of Tetrazine Bioorthogonal Reactivity by Rotaxanation
Control of tetrazine‐mediated inverse electron demand Diels–Alder (IEDDA) reaction has been achieved by rotaxanation. Tetrazine rotaxanes were synthesized in high yield and they displayed a much slower kinetics compared to the corresponding thread. Mechanical bond disassembly upon the right stimulus activates reactivity.
Carlos Fumero‐Medina +10 more
wiley +2 more sources
Summary Carotenoids and apocarotenoids are widespread specialized metabolites, yet animals, including sponges, lack the ability to synthesize carotenoids de novo and must obtain them from dietary or microbial sources. The roles of carotenoid cleavage dioxygenases (CCDs) in marine animals remain largely unexplored. A CCD from the marine sponge Suberites
Elena Moreno‐Giménez +11 more
wiley +1 more source
Bibliometric analysis of Alzheimer's and dementia research in Latin America
Abstract INTRODUCTION Dementia is increasing rapidly in Latin America and the Caribbean (LAC), but research output remains limited. Tracking publication trends, themes, and collaborations is key to guiding regional research and policy. METHODS Bibliometric analysis was conducted on dementia‐related publications from 21 LAC countries (1990 to 2024 ...
Mauricio Vazquez‐Guajardo +7 more
wiley +1 more source
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre +5 more
wiley +1 more source
Crosslinked gelatin‐functionalized PCL scaffolds exhibited enhanced hydrophilicity, structural stability, and porous interactions. In vitro assays demonstrated improved osteoblast adhesion, viability, and proliferation without cytotoxicity, while in vivo evaluation showed no adverse inflammatory response, supporting their potential application in ...
Fernanda Ramírez‐Ruiz +7 more
wiley +1 more source
The landscape of dementia research, diagnosis, treatment, and care in Latin America
Abstract Latin America is undergoing rapid population aging alongside a rising burden of dementia. While the region holds substantial potential for dementia risk reduction, challenges remain, such as delayed diagnoses, limited access to specialized care and biomarker testing, persistent stigma, and deep‐rooted structural inequities.
Claudia K. Suemoto +41 more
wiley +1 more source
Los simuladores como medios de enseñanza en la docencia médica
La simulación en la educación médica ha presentado un desarrollo importante a nivel mundial. Se ha convertido en un medio de enseñanza-aprendizaje mediante el cual se favorece el desarrollo de competencias, especialmente la adquisición de habilidades ...
Yanetsi Contreras Olive +3 more
doaj +2 more sources
Estudios básicos y clínicos sobre la melatonina como ejemplo de medicina traslacional [PDF]
A esta altura de la vida uno se siente tentado a detenerse y reflexionar sobre lo que la vida profesional le ha deparado. En mi caso se cumplen 50 años de mi relación con la glándula pineal y la melatonina y reconozco la inmensa fortuna de haberme ...
Cardinali, Daniel Pedro
core
Bringing together experts in reflux diseases, including gastroenterologists, surgeons, endoscopists, laryngologists, pulmonologists, and research scientists, the inaugural Gatherings in Esophagology (GiE) was held May 30–31, 2025, in France as a new initiative of Organisation mondiale d'Etudes Spécialisées pour les maladies de l'Oesophage (OESO).
Jennifer Cable +38 more
wiley +1 more source
Nineteen international endocrinologists support fenofibrate use to prevent diabetic retinopathy progression and emphasize the need for coordinated care pathways and early intervention to improve diabetic retinopathy management globally. ABSTRACT Background Diabetic retinopathy remains a leading cause of preventable blindness worldwide, yet screening ...
Richard C. O'Brien +9 more
wiley +1 more source

