Reversal of gastrointestinal carcinoma-induced immunosuppression and induction of antitumoural immunity by a combination of cyclophosphamide and gene transfer of IL-12 [PDF]
Immunotherapy-based strategies for gastrointestinal carcinomas (GIC) have been exploited so far, but these approaches have to face strong mechanisms of immune escape induced by tumours.
Alaniz +69 more
core +1 more source
Temporal and spatial expression of genes involved in DNA methylation during reproductive development of sexual and apomictic Eragrostis curvula [PDF]
Recent reports in model plant species have highlighted a role for DNA methylation pathways in the regulation of the somatic-to-reproductive transition in the ovule, suggesting that apomixis (asexual reproduction through seeds) likely relies on RdDM ...
Echenique, Carmen Viviana +9 more
core +1 more source
Spatially Resolved Monitoring of Drying of Hierarchical Porous Organic Networks [PDF]
Evaporation kinetics of water confined in hierarchal polymeric porous media is studied by low field nuclear magnetic resonance (NMR). Systems synthesized with various degrees of cross-linker density render networks with similar pore sizes but different ...
Acosta, Rodolfo Hector +7 more
core +1 more source
Lipids at the crossroad of α-synuclein function and dysfunction: Biological and pathological implications [PDF]
Since its discovery, the study of the biological role ofα-synuclein and its pathologicalimplications has been the subject of increasing interest. The propensity to adoptdifferent conformational states governing its aggregation and fibrillation makes ...
Alza, Natalia Paola +4 more
core +1 more source
Fricke and polymer gel 2D dosimetry validation using Monte Carlo simulation [PDF]
Complexity in modern radiotherapy treatments demands advanced dosimetry systems for quality control. These systems must have several characteristics, such as high spatial resolution, tissue equivalence, three-dimensional resolution, and dose-integrating ...
Chacón Obando, D. +12 more
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Universidad Nacional de Colombia [PDF]
For the first time in its history, the National University of Colombia has a Department of Sociology. Organized temporarily within the Faculty of Economic Sciences, the new department is directed by Orlando Fals Borda, a Colombian sociologist trained in the United States, author of widely known studies of Latin American peasant societies, and since ...
openaire +2 more sources
The spatio-temporal distribution patterns of biting midges of the genus Culicoides in Salta province, Argentina [PDF]
The goal of this survey was to analyze the spatio-temporal distribution patterns of Culicoides Latreille species (Diptera: Ceratopogonidae) and their relationship with environmental variables in Salta, northwestern Argentina.
Dantur Juri, Maria Julia +4 more
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Denitrification-derived nitric oxide modulates biofilm formation in Azospirillum brasilense [PDF]
Azospirillum brasilense is a rhizobacterium that provides beneficial effects on plants when they colonize roots. The formation of complex bacterial communities known as biofilms begins with the interaction of planktonic cells with surfaces in response to
Arruebarrena Di Palma, Andrés +7 more
core +1 more source
New amphiphilic amino acid derivatives for efficient DNA transfection in vitro [PDF]
Nucleic acids-based therapies have recently developed as next-generationagents for treating and preventing viral infection, cancer, and genetic disorders,but their use is still limited due to its relatively poor delivery into targetedcells.
Antuña, Sebastián +7 more
core +1 more source
Circadian rhythms of proliferation events in two mouse carcinomas [PDF]
We studied the index of DNA synthesis (DNAs) of two cellular carcinomas: the hepatocellular ES12a and the mammary TN60 of mice, throughout one circadian cycle.
Andrini, Laura Beatríz +6 more
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