Results 91 to 100 of about 209,872 (209)

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Acute Modafinil Exposure Induces Neurobehavioral Alterations in Zebrafish: Implications for Off‐Label Cognitive Enhancement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado, Nicole Berton, Nicoli da Rosa Amaral, Inara Carbonera Biazus, Laíse Mattiollo, Jéssica Nardi, Karen Júlia de Souza dos Santos, Natália Freddo, Leonardo José Gil Barcellos, Luciana Grazziotin Rossato‐Grando   +9 more
wiley   +1 more source

Transcranial Color‐Coded Duplex Sonography in Large‐Vessel Vasculitis Compatible With Takayasu Arteritis Presenting Intracranial Involvement and Vertebrobasilar Dolichoectasia: A Case Report

Journal of Clinical Ultrasound, EarlyView.
This case illustrates sequential intracranial occlusions in large‐vessel vasculitis compatible with Takayasu arteritis preserving perfusion through robust collateral pathways. Transcranial color‐coded duplex sonography identified characteristic blunted flow patterns and focal turbulence, underscoring its value in detecting hemodynamic compromise beyond
Maria Júnia Lira e Silva, Jordana Gaudie Gurian, Isabella Mesquita Venâncio, Eva Carolina Rocha, Gisele Sampaio Silva   +4 more
wiley   +1 more source

Normal ranges of the fetal weight determined by ultrasound in the population of the Hospital das Clínicas of the Faculdade de Medicina da Universidade de São Paulo. [PDF]

Clinics (Sao Paulo)
Hase EA, Amaral A, Peres SV, Francisco RPV.   +3 more
europepmc   +1 more source

Generative Artificial Intelligence–Driven Clinical Case Simulation in Temporomandibular Disorder Education: ChatGPT Versus Real Patients

Journal of Dental Education, EarlyView.
ABSTRACT Background Temporomandibular disorders (TMDs) and orofacial pain (OFP) demand advanced diagnostic and clinical reasoning skills in dental education. Traditional simulations with real patients face limitations in availability and standardization.
Paula Rodrigues‐Pereira, Maria Amália Pereira Dias‐Calças, Alex Moreira Mélo, Melissa de Oliveira Melchior, Lucas Gaspar Ribeiro, Antônio Pazin‐Filho, Jardel Francisco Mazzi‐Chaves, Laís Valencise Magri   +7 more
wiley   +1 more source

Tales From Within: Dental Students’ Reflective Activities Involving Equity‐Deserving Communities

Journal of Dental Education, EarlyView.
ABSTRACT Objective Undergraduate dental training benefits from community service‐learning (CSL) placements, in which equity‐deserving groups receive oral health care and students can critically reflect on their experiences. This study aimed to thematically explore the moments of revelation and struggle that senior dental students reflected on while ...
Mario Brondani, Renata Paz Leal Pereira, Bebecca Elias   +2 more
wiley   +1 more source

Evaluation of the uptake and usability of the pregnant women surveillance system (SIMG): A cross‐sectional pilot study

International Journal of Gynecology &Obstetrics, EarlyView.
Charles M'poca Charles, Gabriel Valente Tozatti, Cristiano Torezzan, Renato Teixeira Souza, Maria Laura Costa, José Guilherme Cecatti, Rodolfo de Carvalho Pacagnella   +6 more
wiley   +1 more source

Characterisation of Drought and Wet Events in the Paraíba do Sul River Basin—Brazil

International Journal of Climatology, EarlyView.
Trend analysis identified statistically significant reductions in precipitation (at the 5% significance level) at specific pluviometric stations in São Paulo and Rio de Janeiro, while other areas, mainly in Minas Gerais, experienced significant increases in annual and seasonal rainfall, particularly during summer and spring. These significant trends at
Gildo Rafael de Almeida Santana, Eliane Barbosa Santos, Maria Gertrudes Alvarez Justi da Silva, Vicente de Paulo Santos de Oliveira, Jader Lugon Junior   +4 more
wiley   +1 more source

Analysis of Climate Variability of Homogeneous Regions of Rainfall Anomalies in Southeast South America (SESA)

International Journal of Climatology, EarlyView.
We studied rainfall variability and cyclicity in six Homogeneous Regions of Rainfall Anomalies (HRRA) in Southeast South America (SESA) from 1961 to 2020 to understand the occurrence of droughts and above‐average rainfall. We use a continental analysis scale, focusing on seasonal, interannual, and interdecadal cycles, and their association with modes ...
Tainã Costa Peres, Francisco Eliseu Aquino, Denilson Ribeiro Viana, Éder Leandro Bayer Maier, Pedro Teixeira Valente   +4 more
wiley   +1 more source

Upper and small bowel Crohn's disease in Brazilian children: Phenotypic characteristic and surgical risk

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Upper and small bowel Crohn's disease (U‐SBCD) represents a clinically aggressive phenotype with high complication rates yet remains diagnostically challenging. In low‐ and middle‐income countries (LMICs), limited inflammatory bowel disease (IBD) awareness contributes to diagnostic delays, but their impact on U‐SBCD outcomes remains
Jane Oba, Carlos Walter Sobrado, Elizete Aparecida Lomazi, Mariana Deboni, Michela Cynthia da Rocha Marmo, Vanessa Adriana Scheeffer, Silvio da Rocha Carvalho, Adérson Omar Mourão Cintra Damião, Matheus Freitas Cardoso de Azevedo, Carlos Frederico Sparapan Marques, Eytan Wine, Artur Figueiredo Delgado, Clovis Artur Almeida da Silva Full   +12 more
wiley   +1 more source