Results 31 to 40 of about 375,970 (223)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Classe obrera i transició: una visió des de la fàbrica
Segle XX, 2020 El present article té com a objectiu exposar les conclusions principals de la tesi doctoral que porta per títol Models sindicals al món de la fàbrica (1976-1982).
Marta Mulero, Universitat de Barcelona
doaj
Julius-Kühn-Archiv, 2014 Entzündungen sind Reaktionen des Organismus auf die Einwirkung von unterschiedlichen Reizen, die physikalisch chemischer Art sein können, oder auf Infektionserreger und maligne Neoplasmen zurückzuführen sind.
Stuppner, Hermann
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
, 2002 The aim of this study was to compare the internationally known standard ICD 9 with three of its clinical modifications and with SNOMED regarding their usefulness in the field of orthopaedic surgery. The practicality of adaptive documentation (freetext coding) and possibilities of an improvement of the application of ICD-Codes with descriptive codes for
Herrmann, Anne Christine +1 more
openaire +3 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Intel·ligència Artificial i Dret
IDP, 2018 El passat 27 de juny de 2018, el grup de recerca Dret d'Internet - DDI (grup consolidat AGAUR 2017SGR1711), dels Estudis de Dret i Ciència Política de la UOC, va organitzar la jornada «Intel·ligència Artificial i Dret», a la seu de la Universitat Oberta
Raquel Xalabarder
doaj +3 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source