Results 21 to 30 of about 2,244,148 (234)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Temps d'Educació, 2013 El procés de construcció de l'Espai Europeu d'Educació Superior (EEES) no ha estat exempt de controvèrsia i diferents nivells d'interpretació en la seva creació, fonamentació i desenvolupament.
Núria Arís, Miquel Àngel Comas
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Girona, una universitat oberta
, 1992 Imatges de la Universitat i dels actes que s'hi organitzen1194.mp4 1194 ...
Universitat de Girona
core +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Revista Catalana de Dret Públic, 2012 Partint de la transcendència que per a la institució universitària espanyola va tenir la proclamació de la seva autonomia en la Constitució del 1978, el present treball ofereix una crònica en la qual, seguint un criteri material (i no cronològic), s'ha ...
Enriqueta Expósito Gómez
doaj
Revista de Llengua i Dret - Journal of Language and LawAquest estudi quantitatiu explora l’ús de les llengües a la Universitat de Vic-Universitat Central de Catalunya (UVic-UCC) en tres col·lectius –estudiants de grau, personal docent i investigador (PDI) i personal d’administració i serveis (PAS)– durant ...
Sarah Khan +2 more
doaj +1 more source
Censor de Documents d'Anàlisi Geogràfica 2005
Documents d'Anàlisi Geogràfica, 2006 Bru, Josepa Universitat de Girona Burriel, Eugenio Universitat de València Cristóbal, Jordi Universitat Autònoma de Barcelona Estalella, Helena Universitat Autònoma de Barcelona Méndez, Ricardo CSIC Mendizàbal, Enric Universitat Autònoma de Barcelona ...
Editors
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source