Results 241 to 250 of about 2,556,960 (306)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Correction: Integrative omics analysis reveals distinct adaptations of bongkrekic acid producing <i>Burkholderia gladioli pathovar cocovenenans</i> strains. [PDF]

Front Microbiol
He J, Zhao L, Sun Y, Chen Q, Li J, Chen J, Zhang Y, Yang L, Liu Y, Lei L.   +9 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Exploring the Case-Based Learning Challenge (CBLC): a digitally mediated, inter-university simulation to enhance clinical reasoning in physiotherapy students - a quasi-experimental study. [PDF]

BMC Med Educ
Sellitto G, Galeoto G, Deodato M, Di Bari M, Garaventa D, Testa M, Pelosin E, Pillastrini P, Gatti R, Trucco M, Board of Directors of Italian Physiotherapy Degree Course (Conferenza Permanente delle Classi di Laurea delle Professioni Sanitarie).   +10 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Speech speed in audiovisual resources in the learning process of university students: a scoping review.

Codas
Silva KD, Alcantra Cruz PJ, Santos NFC, Jesus FVM, Behlau M, Almeida AA, Guedes-Granzotti RB.   +6 more
europepmc   +1 more source

Breaking the cycle: The legitimacy-building strategies of private universities. [PDF]

Res Comp Int Educ
Buckner E, Yuan S, D'Cruz A.
europepmc   +1 more source

Education as an upstream social security intervention: constructing a competency-based talent development framework in health economics. [PDF]

Front Public Health
Luo H, Li A, Hua H.
europepmc   +1 more source

The phenomenon of ragging: violence among university students in Sri Lanka. [PDF]

Glob Health Action
Wickramasinghe A.
europepmc   +1 more source

Prevalence and Determinants of Hepatitis B Vaccination Coverage Among Medical Students in Tanzania: A Multicenter University-Based Survey. [PDF]

Health Sci Rep
Sindato EM, Mwalimu SM, Nkuwi EJ, Bintabara D.   +3 more
europepmc   +1 more source