Results 61 to 70 of about 1,739,293 (298)

2067 Developing a cultural adaptation of a telephone genetic counseling intervention for Latina women at-risk of hereditary breast and ovarian cancer

Journal of Clinical and Translational Science, 2018
OBJECTIVES/SPECIFIC AIMS: The overall goal of this project is to enhance the use of GCRA in Latina breast cancer survivors at high risk of hereditary breast and ovarian cancer to reduce disparities in GCRA uptake. The aims of the study are to (1) develop
Alejandra Hurtado de Mendoza, Sara Gómez Trillos, Marc Schwartz, Beth Peshkin, Heidi E. Hamilton, Katie Fiallos, Filipa C. Lynce, Susan Vadaparampil, Vanessa B. Sheppard, Lucile Adams-Campbell, Andrea Otero, Kristi Graves   +11 more
doaj   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Isolation and characterization of phosphofungi, and screening of their plant growth-promoting activities

AMB Express, 2018
Rhizospheric microorganisms can increase phosphorus availability in the soil. In this regard, the ability of phosphofungi to dissolve insoluble phosphorus compounds is greater than that of phosphate-solubilizing bacteria. The aim of the current study was
Xiaohui Wang, Changdong Wang, Junkang Sui, Zhaoyang Liu, Qian Li, Chao Ji, Xin Song, Yurong Hu, Changqian Wang, Rongbo Sa, Jiamiao Zhang, Jianfeng Du, Xunli Liu   +12 more
doaj   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Pemahaman Matematis Siswa Dengan Menggunakan Buku Elektronik Interaktif Berbantuan Geogebra

JNPM (Jurnal Nasional Pendidikan Matematika), 2019
Perkembangan teknologi dalam pendidikan dapat digunakan untuk memberikan inovasi dalam pembelajaran matematika, salah satunya yaitu adanya buku elektronik yang interaktif.
Kadek Surya Octamela, Gede Suweken, I Made Ardana   +2 more
doaj   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

3477 Impaired emotion recognition accuracy after right-hemisphere stroke

Journal of Clinical and Translational Science, 2019
OBJECTIVES/SPECIFIC AIMS: Every year, approximately 800,000 Americans suffer a stroke. Supportive social environments are recognized as an important factor contributing to successful stroke recovery, yet, stroke lesions can affect brain areas important ...
Katherine OConnell, Abigail A. Marsh, Anna Greenwald   +2 more
doaj   +1 more source

A National University [PDF]

Science, 1886
n ...
openaire   +3 more sources

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source

The University, the Universe, the World, and ?Globalization?

The Global South, 2007
Gramma: Journal of Theory and Criticism, Vol 13 (2005): Comparative Literature & Global ...
openaire   +3 more sources