Results 91 to 100 of about 1,432,495 (305)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

University Funding Policies: Buildings or Citizens? [PDF]

open access: yes, 2013
Governments tend to fund universities based on the number of registered students and lump sum transfers. Such policy induces universities to compete for recruiting students, diverting money away from funds devoted to teaching.
Bouchard St-Amant, Pier-André
core  

Inferring Room Semantics Using Acoustic Monitoring

open access: yes, 2017
Having knowledge of the environmental context of the user i.e. the knowledge of the users' indoor location and the semantics of their environment, can facilitate the development of many of location-aware applications.
Harras, Khaled A.   +2 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Assessing the impact of the COVID-19 lockdown on the energy consumption of university buildings. [PDF]

open access: yesEnergy Build, 2022
Gaspar K   +6 more
europepmc   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

FREE SOFTWARE IN THE «3D MODELS IN GOOGLE EARTH» PROJECT [PDF]

open access: yes, 2017
The "3d models in Google Earth" project there was in О. М. Beketov National University of Urban Economy in Kharkiv since 2010. In the Google Earth free software, 3D models of buildings and structures included in the layer "the best 3D buildings" are ...
Клименко, Роман
core  

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