Results 21 to 30 of about 508,650 (215)

A multi-dimensional assessment of campus public open spaces in Indian technical universities using the campus open space index (COSI)

open access: yesFrontiers in Built Environment
IntroductionPublic open spaces in university campuses support social interaction, mental wellbeing, informal learning, and academic engagement. However, many campus public open spaces in Indian technical universities remain underused because of limited ...
Nazish Abid   +5 more
doaj   +1 more source

Depression restoration in university students: Data-driven insights across three types of campus greennessOSF

open access: yesData in Brief
This data examines the relationship between campus green spaces and university students’ mental health, focusing on their restorative potential and the factors influencing engagement.
Chaoyi Cui, Qianchen He, Huiming Liu
doaj   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen   +21 more
wiley   +1 more source

Immunoglobulin Depletion and Recovery Following Blinatumomab in Infants With KMT2A‐Rearranged ALL

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Adding blinatumomab to standard chemotherapy for infants with KMT2A‐rearranged acute B‐cell lymphoblastic leukemia (KMT2A‐r B‐ALL) improves outcomes. Although blinatumomab impairs immunoglobulin G (lgG) production, increasing infection susceptibility, IgG recovery remains poorly understood.
Miguel Vieira Martins   +14 more
wiley   +1 more source

Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel   +15 more
wiley   +1 more source

Smartphone GPS Locations of Students’ Movements to and from Campus

open access: yesISPRS International Journal of Geo-Information, 2021
For many university students, commuting to and from campus constitutes a large proportion of their daily movement, and therefore it may influence their ability and willingness to spend time on campus or to participate in campus activities.
Patricia K. Doyle-Baker   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A Typological Study of the Socio-Spatial Composition of New-Type Universities in China: A Case of SUSTech Campus

open access: yesBuildings
As pioneers in the reform of higher education in China, China’s new-type universities, often referred to as the fourth generation of universities, play a crucial role in driving the iteration of educational concepts and innovation in planning and design ...
Tianjia Wang   +9 more
doaj   +1 more source

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