Results 81 to 90 of about 16,285,142 (304)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Pedagogical education for university teachers in Finland

open access: yesRed U, 2013
En Finlandia la formación pedagógica es un requerimiento para todos los niveles de la profesionalidad docente, desde la Escuela Infantil hasta las Escuelas Politécnicas, exceptuada la universidad.
Mari Murtonen, Matti Lappalainen
doaj  

Advancement, Fall 2001 [PDF]

open access: yes, 2001
Advancement, a supplement to Bostonia magazine, provided updates on BU development activities, including major gifts and ...
Boston University Office of Development and Alumni Relations
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

A Contribuição da universidade pública para a inovação e o desenvolvimento regional: a percepção de gestores e pesquisadores

open access: yesRevista Gestão Universitária na América Latina, 2013
This article presents a case study about the Polo Universitário de Volta Redonda (PUVR-UFF), a new campus of Federal Fluminense University (UFF), located in the Médio Paraíba Fluminense Region (RMP-RJ). The aim is to identify the limits and possibilities
Maria Antonieta Leopoldi   +1 more
doaj   +2 more sources

Creando Pensamus: scientific research is future’s driving force

open access: yesAgathón, 2018
Italy should go back to a University that has an institutional status, as Piero Calamandrei desired: an institution that could teach the ideas of free thought and tangible action. A University that could be an education agency, transforming resources and
Maurizio Carta
doaj   +1 more source

Online Catalog Development at the University of Guelph [PDF]

open access: yes, 1987
published or submitted for ...
Beckman, Margaret
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Lingnan Gardeners Bimonthly Newsletter (No. 47) = 嶺南彩園通訊 (第47期)

open access: yes, 2019
Balsamines 鳳仙花https://commons.ln.edu.hk/ln_gardeners_newsletter/1047/thumbnail ...
Lingnan Gardeners, Kwan Fong Cultural Research and Development Programme, Lingnan University
core   +2 more sources

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