Results 131 to 140 of about 84,423,094 (271)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Digital ergonomics and digital work planning in university education: experiences from Germany and Austria. [PDF]
Z Arbeitswiss, 2022 Schlund S +10 more
europepmc +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
University students' perceptions of their readiness to enter the workforce upon graduation [PDF]
, 2004 xi, 135 leaves ; 29 cm.The purpose of this study was to explore and gain a greater understanding of senior university students' perceptions of their readiness to enter the work force following program completion, as well as their perceptions of the ...
Archer, Christie +1 more
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Derrida, Butler and an Education in Otherness [PDF]
, 2009 Proceedings of the 2nd International Colloquium between the Graduate School of Education, Kyoto University (Japan) and the Institute of Education, University of London (UK) : 28 February- 1 March 2009 Kyodai Kaikan Kyoto ...
Ian Munday, Munday, Ian
core
Revista de la Asociación Odontológica Argentina, 2019 Resumen El uso de las nuevas tecnologías en la enseñanza universitaria no consiste solo en emplear dispositivos o softwares, sino que involucra cambios en por lo menos tres ejes: nuevas relaciones con el conocimiento, la transformación de la didáctica y
Cecilia Sagol
doaj
To capture the research landscape of lecture capture in university education. [PDF]
Comput Educ, 2021 Banerjee S.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source