Results 71 to 80 of about 9,523,290 (285)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Symbolic Employment of Contemporary Ceramic Work structure between shape and content

open access: yesJournal of Architecture, Art & Humanistic Science
Art work has sought with the advent of the 20th century to avoid visual reality and move closer to aesthetic and plastic values to up grade the worth of work content and invest figural appearances to meet such objective in light of the above numerous ...
Dr. Amira Ahmed Mohamed Essawy Lecturer Instructor of Ceramics, Embodied Expression Department, Art Education College, Helwan University
doaj   +1 more source

Multicultural society from view of university students

open access: yesJournal of Language and Cultural Education, 2016
The article focuses on exploring the way in which Slovakia is viewed as a multicultural society by sampling university students with a survey. For that reason, the aim was to examine the extent that participation in the educational process at university ...
Sirotová Mariana   +1 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Inter university cooperation and social education. multicultural frame and joint curricula [PDF]

open access: yes, 2014
1. No doubt about being upper levels in education a prioritarian way for the universalization of knowledge, as the authors more than once argued (see their Presentation at the previous Conference on Education 2012) 2.
BENVENUTO, Guido, VEGGETTI, Maria Serena
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Ten years of the Waikato Journal of Education. [PDF]

open access: yes, 2004
The article reports on the 10th volume of 2004 Waikato Journal of Education, a cause for celebration and special comment. The journal's origins are closely linked to the origins of the School of Education at the University of Waikato.
McGee, Clive
core   +1 more source

Introduction to special edition. [PDF]

open access: yes, 2010
This special issue of the Waikato Journal of Education arose from a symposium held at The University of Waikato in June, 2009. The symposium, Initial Teacher Education and the New Zealand Curriculum–Te Marautanga o Aotearoa Symposium, was attended by ...
Cooper, Beverley, McGee, Clive
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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