Results 111 to 120 of about 1,443,544 (307)

Understanding (In) Effective Presidential Leadership: Board Members’ Perspectives

open access: yesEducation Sciences
This qualitative study examines trustees’ perspectives on effective presidential leadership in higher education institutions in Kazakhstan and the United States.
Aida Sagintayeva   +2 more
doaj   +1 more source

[Review of] Charles V. Willie and Ronald R. Edmonds (Eds.). Black Colleges in America: Challenge, Development, Survival [PDF]

open access: yes, 1979
This book is a collection of articles from the Black College Conference held at Harvard University in March and April of 1976. The authors are experienced administrators, teachers, and students of our nation\u27s black colleges and universities.
Lipscomb, LaFayette W.
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Book review: accelerating democracy: transforming governance through technology [PDF]

open access: yes, 2013
John O. McGinnis demonstrates how new technologies combine to address a problem as old as democracy itself: how to help citizens better evaluate the consequences of their political choices.
Alonso, Ana Polo
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Governança na pesquisa científica: reflexões sobre a prática da pesquisa contemporânea e a experiência brasileira

open access: yesSociologias
Resumo Tradicionalmente, a literatura sociológica faz uma clara distinção entre as abordagens que analisam o ensino superior e as mudanças que este vem experimentando nas últimas décadas, e as abordagens que analisam os fatos sociais relacionados à ...
Elizabeth Balbachevsky
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Book review: Divided nations: why global governance is failing and what we can do about it [PDF]

open access: yes, 2013
"Divided Nations: Why Global Governance is Failing and What We Can Do About It." Ian Goldin. Oxford University Press. March 2013. --- Humanity today faces a number of international challenges which spill over national boundaries: climate change, finance,
Hearson, Martin
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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