Results 121 to 130 of about 7,831,010 (335)
Special connections: January 14, 1991 [PDF]
, 1991 Time-sensitive news update to monthly University Hospital ...
Office of Publication Services, Boston University Medical Center
core
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Presentations of Sultan Qaboos University Clinico-Pathologic Conferences
Sultan Qaboos University Medical Journal, 2015 Sultan Qaboos University College of Medicine & Health Sciences and Sultan Qaboos University Hospital, 2014–2015
doaj +1 more source
Travel and Transportation-Spinal Cord Injury Manual [PDF]
, 2009 Introduction Travel and transportation includes driving or being a passenger in a car or van, or traveling in an airplane, bus, train or ship. After a spinal cord impairment, traveling for business or pleasure can be an overwhelming experience.
Thomas Jefferson University Hospital and Magee Rehabilitation,
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
LABRAD : Vol 34, Issue 2 - May 2009 [PDF]
, 2009 Acute Leukemia Immunophenotyping with Pakistani Perspective PAX5: Immunohistochemistry Marker for B cell Lymphoproliferative Disorders Understanding the Water Deprivation Test Gonadotropins Releasing Hormone (GnRH) Stimulation Test Haematology Quiz Red ...
Aga Khan University Hospital, Karachi
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source