Results 121 to 130 of about 6,331,415 (309)
Baseline study: nutritional status, food security and fish consumption among people living with HIV/AIDS in Zambia [PDF]
Under the regional programme Fisheries and HIV/AIDS in Africa, the University of Zambia, in collaboration with the WorldFish Center, has undertaken a baseline survey of the nutritional status and fish consumption of people living with HIV/AIDS in Zambia.
Banda Nyirenda, D. +2 more
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Persistent andragogical patterns across the generations: From university tutorial classes to postgraduate online education [PDF]
, 2017 The concept of design patterns in education raises the question of whether their validity can persist over a period of time or whether social and technological change means that yesterday’s virtues are today’s irrelevancies.
Kingsley , Paul
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Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Strengthening Uganda's policy environment for investing in university development [PDF]
The authors examine the policy environment for investment in university development in Uganda, with special attention to the needs of Makerere University. They present data on the structure and financing of higher education, which gets a high priority in
Colletta, Nat +7 more
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Tagore and the academic study of religion [PDF]
, 2016 Rabindranath Tagore (1861–1941), at about the start of the nineteenth century, was advocat‐ ing that the study about religion has to be included in university‐level education in the East.
Khan, Abrahim H.
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Project report – transferable skills in higher education [PDF]
, 2005 This study was initiated by the need, frequently expressed by employers, for the education system to produce potential employees with better transferable skills. The paper reports a field trial at a UK university (following a four-year pilot of NVQ Level
Dennis, C, Wadsworth, D
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source