Results 71 to 80 of about 85,798,543 (234)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

BALANCED SCORECARD NA GESTÃO UNIVERSITÁRIA: MAPEAMENTO SOBRE O TEMA UTILIZANDO O PROKNOW-C

open access: yesRevista Gestão Universitária na América Latina, 2015
The growing importance of higher education in economic and social scenario has forced universities to improve their management methods, and one of the forms used has been the application of the Balanced Scorecard.
Lucas dos Santos Matos   +1 more
doaj  

Country Differences in the Internationalization of Higher Education – How can Countries Lagging behind Diminish the Gap [PDF]

open access: yesRevista de Management Comparat International, 2009
This paper looks at the internationalization of higher education in a number of countries with the final purpose to make proposals for the acceleration of the higher education internationalization process of the countries that lag behind. It does that by
Luminiţa NICOLESCU   +2 more
doaj  

PERFIL E PERSPECTIVAS DOS EGRESSOS DO CURSO DE ADMINISTRAÇÃO DA UFFS: UM ESTUDO REALIZADO NO CAMPUS CHAPECÓ/SC

open access: yesRevista Gestão Universitária na América Latina, 2019
This article aims to analyze the profile and prospects of the graduates of the administration course of UFFS – Campus Chapecó/SC, as well as their contribution to the evaluation of the course and university.
Camila Giacomin   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

UNIVERSIDADE PÚBLICA, DEMOCRÁTICA E POPULAR: OS DESAFIOS DA IMPLANTAÇÃO DA UNIVERSIDADE FEDERAL DA FRONTEIRA SUL

open access: yesRevista Gestão Universitária na América Latina, 2011
This article aims to present the process of implementation of the Universidade Federal da Fronteira Sul from some of the conditions of its implementation (context lines), the outlined concept of a public, democratic and popular university (concept) and ...
Vicente de Paula Almeida Júnior   +1 more
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Model of relationship of transformational leadership and university management

open access: yesDyna, 2019
We propose to find the model of relationship between Transformational Leadership and university management. The Inventory of Leadership Practices form was used (LPI) and an University Management (UG) scale, which consists of four dimensions: Research ...
Zahira Moreno Freites   +1 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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