Results 21 to 30 of about 4,340,742 (292)

Platform Competition: The Role of Multi-homing and Complementors [PDF]

, 2006
In this paper we present a model of platform competition in which two firms offer horizontally differentiated platforms and a group of complementors offers products that are complementary to each platform.
Carrillo, Juan D. - University of Southern California, Tan, Guofu - University of Southern California   +1 more
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Decolonizing the Curriculum? Unsettling possibilities for performance training

Revista Brasileira de Estudos da Presença, 2018
TThis essay problematizes the term ‘decolonization’ as applied to university dance and performance curricula. It does so via Eve Tuck and K. Wayne Yang’s (2012) argument that colonization is rooted in a worldview that positions beings as exploitable ...
Janet O'Shea (University of California – UCLA, Los Angeles, United States of America)
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Switching Costs in Network Industries [PDF]

, 2009
In network industries, switching costs have two opposite effects on the tendency towards market tipping. First, the fat-cat effect makes the larger firm price less aggressively and lose consumers to the smaller firm. This effect tends to prevent tipping.
Chen, Jiawei - University of California, Irvine
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Decolonizar o Currículo? Possibilidades para desestabilizar a formação em performance

Revista Brasileira de Estudos da Presença, 2018
Este ensaio problematiza o termo decolonização aplicado aos currículos de dança e performance no ensino superior. Para tanto, utiliza o argumento de Eve Tuck e K.
Janet O’Shea (University of California – UCLA, Los Angeles, Estados Unidos da América)
doaj  

How Do Mobile Information Technology Networks Affect Firm Strategy and Performance? Firm-Level Evidence from Taxicab Fleets [PDF]

, 2006
This paper examines how the adoption of mobile information technology networks impact firm strategy and performance in the U.S. taxicab industry.
Rawley, Evan - University of California, Berkeley
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Defunding Higher Education: What Are the Effects on College Enrollment? [PDF]

, 2012
Examines the effects of the state's higher education spending cuts on enrollment rates of eligible, highly prepared students at the University of California, California State University, and California Community Colleges systems.
Hans P. Johnson
core