Results 81 to 90 of about 188,369,412 (295)

California College of Medicine

open access: yes, 1968
Scenes of construction of California College of Medicine (CCM) at California Ave. and Bridge Road.
University of California, Irvine, University Relations
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Preliminary Announcement: University of California, Irvine, Academic Program 1965-1966

open access: yes, 1965
A brochure outlining the academics, enrollment, and student services for the University of California, Irvine campus for the 1965-1966 academic year.
University of California, Irvine
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Antitranspirants …uses and effects on plant life

open access: yesCalifornia Agriculture, 1969
This review of recent research data on application, effects and potential uses for antitranspirants in plant growth shows particular possibilities for conserving irrigation water, aiding plant survival under dry conditions, and protecting foliage against
D Davenport, R Hagan, P Martin
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Tobacco Use in California, 1990 [PDF]

open access: yes, 1991
SummaryThis report presents data on a partial sample of a survey of cigarette smoking behaviors and attitudes among Californians conducted during the summer of 1990. The prevalence of current smoking among adults in California is 21.2%, with males (23.8%)
California Department of Health Services   +1 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

José C. Moya, Cousins and Strangers; Spanish Immigrants in Buenos Aires 1850-1930. / Jeffrey Lesser: Welcoming the Undesirables: Brazil and the Jewish Question

open access: yesAnuario Colombiano de Historia Social y de la Cultura, 1998
José C. Moya, Cousins and Strangers; Spanish Immigrants in Buenos Aires 1850-1930. Berkeley-Los Angeles-London: University of California Press 1998. 567 páginas. /  Jeffrey Lesser: Welcoming the Undesirables: Brazil and the Jewish Question.
Thomas Fischer
doaj   +2 more sources

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