Results 141 to 150 of about 20,422 (254)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Pursuing University World Rankings: the Balance Between Researching and Teaching for University Faculty

, 2016
The development of higher education is an important index to a nation’s economic and social progress. As a result, most governments would allocate huge amount of budget to upgrade the performances of higher education.
Lii, Peirchyi
core  

A Review on the Major Global University Ranking Systems and the Turkish Universities’ Overall Position in Rankings

Educational Administration: Theory and Practice, 2017
Amidst the increasingly competitive environment in the field of higher education, world ranking systems have gained more research attention in recent years. In this article, the main objectives are to attract attention of especially Turkish academics and policy makers to university ranking systems in the world and to show the overall position of ...
openaire   +3 more sources

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Moving beyond university rankings: developing a world class university system in Australia

, 2010
This paper examines why the development of a world class university system represents a rational, even inevitable, policy approach for Australia in response to world university rankings.
Sheil, Tony
core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Winthrop Included in International Sustainability Rankings

, 2014
In the rankings Winthrop placed 203 out of 301 worldwide institutions and placed 42 out of the 50 U.S. colleges and universities on the list. Winthrop was the only South Carolina university included in the rankings.
Winthrop University
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Wyścig do marki uczelni przyjaznej dla klimatu. Studium Uniwersytetu Jagiellońskiego w rankingach szkół wyższych odpowiedzialnych środowiskowo

Zarządzanie w Kulturze
The paper addresses the issue of the potential impact of a university’s presence in the rankings of climate friendly HEIs on its brand and activities, filling a research gap in this area.
Michał Pałasz
doaj   +1 more source