Results 41 to 50 of about 120,088 (268)

Quantitative Determination of 3-O-Acetyl-11-Keto-βBoswellic Acid (AKBA) and Other Boswellic Acids in Boswellia sacra Flueck (syn. B. carteri Birdw) and Boswellia serrata Roxb

Molecules, 2016
Boswellia serrata and Boswellia sacra (syn. B. carteri) are important medicinal plants widely used for their content of bioactive lipophilic triterpenes.
Giuseppe Mannino, Andrea Occhipinti, Massimo E. Maffei   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Work smart, not hard: analysis of delays faced by clinical trials investigating spinal fusion using Protocol AI

Frontiers in Surgery
IntroductionDegenerative diseases of the spine are increasingly prevalent with age. Spinal fusion is a common treatment if non-invasive or less-invasive treatment approaches have not been successful.
Katia Schiegg, Philipp Khlebnikov, Florian Meer, Joel Kühl, Poorya Amini, Janine Antonov, Emin Aghayev, Emin Aghayev, Stephan Radzanowski, Quentin Haas   +9 more
doaj   +1 more source

Quantifying the Effects of Ethanol and Temperature on the Fitness Advantage of Predominant Saccharomyces cerevisiae Strains Occurring in Spontaneous Wine Fermentations

Frontiers in Microbiology, 2018
Different Saccharomyces cerevisiae strains are simultaneously or in succession involved in spontaneous wine fermentations. In general, few strains occur at percentages higher than 50% of the total yeast isolates (predominant strains), while a variable ...
Donatella Ganucci, Simona Guerrini, Silvia Mangani, Massimo Vincenzini, Lisa Granchi   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Reducing systematic review burden using Deduklick: a novel, automated, reliable, and explainable deduplication algorithm to foster medical research

Systematic Reviews, 2022
Background Identifying and removing reference duplicates when conducting systematic reviews (SRs) remain a major, time-consuming issue for authors who manually check for duplicates using built-in features in citation managers.
Nikolay Borissov, Quentin Haas, Beatrice Minder, Doris Kopp-Heim, Marc von Gernler, Heidrun Janka, Douglas Teodoro, Poorya Amini   +7 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Effect of poly(ethylene glycol)-based cross-linker length on the physicochemical and rheological properties of hyaluronic acid hydrogels potentially applicable in the biomedical field

Carbohydrate Polymer Technologies and Applications
The development of safe and effective hyaluronic acid-based materials is one of the main research focuses for biomedical applications. However, so far, an investigation of the influence of the cross-linker chain length on the physicochemical, mechanical,
Fabiana Cordella, Giuseppe Alonci, Gaetano Angelici, Roberto Mocchi, Martina Savona, Giulia Grimaldi, Giulia Galasso, Sabrina Sommatis, Celia Duce, Elena Pulidori, Elisa Martinelli, Nicola Zerbinati   +11 more
doaj   +1 more source

Flat Array Antennas for Ku-Band Mobile Satellite Terminals

International Journal of Antennas and Propagation, 2009
This work presents the advances in the development of two innovative flat array antennas for Ku-band mobile satellite terminals. The first antenna is specifically conceived for double-deck trains to allow a bi-directional high data rate satellite link ...
Roberto Vincenti Gatti, Luca Marcaccioli, Elisa Sbarra, Roberto Sorrentino   +3 more
doaj   +1 more source