Results 111 to 120 of about 6,058,548 (257)

Factors influencing unmet need for health care services in Korea

open access: yes, 2015
This study was conducted to investigate the prevalence of unmet need based on both subjective assessment and adjustments for need-predicted utilization and to examine factors associated with them.
김태현, 박은철
core   +1 more source

Programmable Variable‐Stiffness Multilayer Elastomer Composites With High‐Aspect‐Ratio Low‐Melting‐Point Alloy Inclusions

open access: yesAdvanced Materials Technologies, EarlyView.
High‐aspect‐ratio low‐melting‐point alloy inclusions are embedded within multilayer silicone laminates to create thermally programmable stiffness. Sequential activation of alloy‐rich layers produces four distinct mechanical states and reconfigures tendon‐driven actuator trajectories under the same load.
Palpolage Don Shehan Hiroshan Gunawardane   +4 more
wiley   +1 more source

A Self‐Healing Permanent Magnet Putty for Soft Robot Skins With Force Sensing and Functional Recovery

open access: yesAdvanced Robotics Research, EarlyView.
Permanent magnet putty (PMP) integrates high‐coercivity NdFeB particles with a dynamic polyborosiloxane–Ecoflex matrix, achieving rapid self‐healing (90% mechanical recovery in 10 s) and magnetic recovery within 20 min. With twice the sensitivity of commercial putties, PMP enables precise 5–30 N force detection and discrimination between pressing and ...
Ruotong Zhao   +5 more
wiley   +1 more source

Liquid Crystalline Elastomers in Soft Robotics: Assessing Promise and Limitations

open access: yesAdvanced Robotics Research, EarlyView.
Liquid crystalline elastomers (LCEs) are programmable soft materials that undergo large, anisotropic deformation in response to external stimuli. Their molecular alignment encodes directional actuation in a monolithic structure, making them long‐standing candidates for soft robotic systems.
Justin M. Speregen, Timothy J. White
wiley   +1 more source

Gender differences in cost-related unmet healthcare needs: a national study in Turkiye

open access: yesBMC Public Health
Background Unmet healthcare needs are a complex and multifaceted issue, influenced by individual, socioeconomic, and healthcare system factors. This study aimed to investigate the determinants influencing cost-related unmet healthcare needs within the ...
Aslı Davas, Nilay Etiler
doaj   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

open access: yesAdvanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang   +5 more
wiley   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

open access: yesAdvanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan   +17 more
wiley   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

open access: yesAdvanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green   +15 more
wiley   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

open access: yesAdvanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang   +6 more
wiley   +1 more source

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