Results 81 to 90 of about 871 (207)

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Intersecting inequities: a scoping review of the gendered relationship between unpaid care work and intimate partner violence during the COVID-19 lockdown in Canada

Global Health Action
Background While there is now extensive research on how COVID-19 lockdowns negatively affected unpaid care burdens and intimate partner violence (IPV), the structural determinants shaping both experiences are less well understood.
Alexandra Beukens, Julia Smith
doaj   +1 more source

Analog Classification of Human Hand Gestures Exploiting Dendritic Integration With an Organic Artificial Soma

Advanced Functional Materials, EarlyView.
An organic neuromorphic architecture for the classification of human motor behavior is presented and validated. It performs somatic integration by linearly combining the activity from three muscles. An investigation of synaptic weights is presented and discussed in relationship with the classification performance.
Ilenia Sergi, Federico Rondelli, Francesco Torricelli, Federica Velluto, Anna De Salvo, Michele Di Lauro, Luciano Fadiga, Fabio Biscarini   +7 more
wiley   +1 more source

Degradable, Skin‐Conformal Nanocomposite‐Based Bioelectronic Patches for High‐Fidelity Electrophysiology and Gesture‐Controlled Robotics

Advanced Functional Materials, EarlyView.
A degradable, skin‐conformal bioelectronic patch combines a starch‐dominated nanocomposite conductor with a gelatin substrate to enable sensitive strain sensing, high‐fidelity electrocardiography, electromyography, electrooculography, and machine‐learning‐assisted gesture control.
Ming Dong, Hongna Yuan, Shubo Liu, Abdulkadir Sanli, Emiliano Bilotti, Han Zhang, Pietro Cataldi, Karin Hing, Oliver Fenwick, Colin J. Humphreys, Dimitrios G. Papageorgiou   +10 more
wiley   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source

Rational Control of Antibody Orientation for Enhancing Sensitivity and Specificity in Lateral Flow Immunoassays With Clinical Validation

Advanced Healthcare Materials, EarlyView.
Systematic investigation of antibody orientation strategies in lateral flow immunoassays reveals that a para‐substituted (aminomethyl)phenylboronic acid mediated probe (P‐6) combined with a biotin‐streptavidin test‐line modification achieves a synergistic 14‐ to 19‐fold sensitivity gain over conventional conjugation. Furthermore, multiplexed detection,
Pin‐Hao Wang, Shunmuga Nathan Shunmuga Nainar, Bing‐Han Zhuang, Shun‐Mao Yang, Hong‐Cheu Lin, Yang‐Hsiang Chan   +5 more
wiley   +1 more source

Conformal Thermoreversible Gelatin‐Based Gel for High‐Fidelity Electrophysiological Recording and Acute Peripheral Nerve Interfacing

Advanced Materials, EarlyView.
A thermoreversible gelatin‐based gel forms a soft, conformal bioelectronic interface on complex biological surfaces. The flowable precursor penetrates hair‐dense regions, solidifies in situ, and maintains low impedance through adaptive contact and hydration retention.
Ruinan Hao, Yong Yuan, Jie Gao, Tong Wang, Jinzhi Du, Feng Tian, Xiaoli Li, Ruirui Qiao, Liqun Zhang, Jiajia Xue   +9 more
wiley   +1 more source

The Digitalization of Social Care in England and Implications for Older, Unpaid Carers: Constructionist Thematic Analysis

Journal of Medical Internet Research
BackgroundGlobally, populations are aging, generating concerns about the sustainability of health and social care provision. In terms of the public provision of social care in particular, unpaid carers provide much of the support ...
Anastasia Rousaki, Efpraxia D Zamani, Laura Sbaffi, Kate Hamblin, Rachael Black   +4 more
doaj   +1 more source

Making Policy Care: A guide to influencing on unpaid care [PDF]

, 2018
This guide aims to capture valuable experiences and learning on influencing activities on unpaid care and domestic work from across the WE-Care programme and several other relevant Oxfam country experiences, and to communicate it in an accessible, practical format that maximizes use for internal and external audiences.
openaire   +1 more source