Results 231 to 240 of about 97,810,316 (272)

Dynamics of bicoid mRNA localisation and translation dictate morphogen gradient formation. [PDF]

EMBO J
Athilingam T, Wilby EL, Bensidoun P, Trullo A, Verbrugghe M, Dufourt J, Shi X, Lagha M, Saunders TE, Weil TT.   +9 more
europepmc   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

Advanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu, Wanying Xiang, Xinyue Wang, Yue Pan, Jing Gao, Jiezhen Yang, Yufei Wang, Zhipu Zhu, Man Tong, Lei Jin, Yan Ye   +10 more
wiley   +1 more source

Ribosome dynamics at the conserved PGP motif governs 2A peptide-bond-skipping efficiency. [PDF]

Nucleic Acids Res
Wu X, Uematsu S, Wu Y, Qian SB.
europepmc   +1 more source

AI‐Assisted Tumor Boundary Delineation via Targeted Ultrasmall Iron Oxide Nanoprobe for High‐Contrast HER2‐Positive Tumor Imaging

Advanced Science, EarlyView.
A novel targeted and pH‐responsive MRI contrast agent was integrated with a 3D nnU‐Net deep learning framework to enable accurate delineation of tumor boundary morphology in HER2‐positive breast cancer imaging. ABSTRACT Breast cancer continues to be a leading cause of cancer‐related mortality in women globally, where precise diagnosis and clear tumor ...
Jiaying Zheng, Yi Zhu, Xinrui Li, Sunxian Dai, Xiangyuan Ma, Hongwei Lu, Zhongling Wang, Benqing Zhou   +7 more
wiley   +1 more source

CT image generation from ultrashort echo time MRI for dosimetric assessment in lung cancer radiotherapy. [PDF]

Phys Imaging Radiat Oncol
Zheng K, Xue X, Zhang Q, Zhou F, Xu J, Wang X, Song X, Mao W, Yuan Z, Liu Y.   +9 more
europepmc   +1 more source

CHST1 Drives Immunotherapy Resistance in Triple‐Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF–CCL20–Macrophage Axis

Advanced Science, EarlyView.
Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang, Xiao‐Han Ying, Ruo‐Qing Wang, Qun Zhang, Li Chen, Zhi‐Ming Shao, Jun‐Jie Li   +6 more
wiley   +1 more source

Traumatic brain injury recovery prediction by harmonizing real brain CT and synthetic brain MRI: a pilot study. [PDF]

Brain Commun
Che Y, Joshi AM, Shah J, Rahman Siddiquee MM, Chong CD, Nikolova S, Dumkrieger G, Li B, Wu T, Schwedt TJ.   +9 more
europepmc   +1 more source

The role of FMR1 mRNA structure on the efficiency of non-canonical translation of toxic polyglycine protein. [PDF]

Nucleic Acids Res
Niewiadomska D, Piasecka A, Baud A, Broniarek I, Sobczak K.   +4 more
europepmc   +1 more source

Slirp2 modulates oogenesis via regulating mitochondrial protein translation. [PDF]

J Mol Cell Biol
Cao J, Zhang J, Wu Z, Luan W, Zhou Y, Huang H, Li L, Hu W.   +7 more
europepmc   +1 more source