Results 71 to 80 of about 2,522,188 (370)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

A modified VIM for solving an inverse heat conduction problem

open access: yesپژوهش‌های ریاضی, 2016
In this paper, we will use a modified  variational iteration method (MVIM) for solving an inverse heat conduction problem (IHCP). The approximation of the temperature and the heat flux at  are considered.
M Rostamian, A. M. Shahrezaee
doaj  

Hygroscopic behavior of atmospheric aerosols containing nitrate salts and water-soluble organic acids [PDF]

open access: yesAtmospheric Chemistry and Physics, 2018
While nitrate salts have critical impacts on environmental effects of atmospheric aerosols, the effects of coexisting species on hygroscopicity of nitrate salts remain uncertain.
B. Jing   +11 more
doaj   +1 more source

Unstable angina pectoris

open access: yesClinical Cardiology, 1990
AbstractThe pathophysiology of unstable angina has been better elucidated in the past five years and has led to more rational therapy. Coronary arteries in patients with unstable angina have atherosclerotic plaques which are often complex and are the site of platelet activation and fibrin deposition.
W A, Wallace, J F, Richeson, P N, Yu
openaire   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Hygroscopicity of organic compounds from biomass burning and their influence on the water uptake of mixed organic ammonium sulfate aerosols [PDF]

open access: yesAtmospheric Chemistry and Physics, 2014
Hygroscopic behavior of organic compounds, including levoglucosan, 4-hydroxybenzoic acid, and humic acid, as well as their effects on the hygroscopic properties of ammonium sulfate (AS) in internally mixed particles are studied by a hygroscopicity tandem
T. Lei   +4 more
doaj   +1 more source

iPSCs: Unstable Origins?

open access: yesMolecular Therapy, 2011
The advent of induced pluripotent stem cell (iPSC) technology holds great promise to revolutionize personalized cell-based therapies.1,2,3,4,5 Recent advances in gene transfer technology therefore open up exciting possibilities for efficient and safe genetic modification of autologous cells in this context.6 As potential therapeutic applications are ...
Mukherjee, Sayandip, Thrasher, Adrian J
openaire   +2 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Elucidating HONO formation mechanism and its essential contribution to OH during haze events

open access: yesnpj Climate and Atmospheric Science, 2023
Atmospheric nitrous acid (HONO) chemistry is of critical importance to air quality during polluted haze events, especially in China. However, current air quality models (such as WRF-CHEM, WRF-CMAQ, Box-MCM) generally underestimate the concentration of ...
Xinran Zhang   +11 more
doaj   +1 more source

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