Results 31 to 40 of about 1,248,702 (199)

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

open access: yesAdvanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu   +10 more
wiley   +1 more source

Memory-Dependent Derivative Versus Fractional Derivative (IV): Space-Dependent Derivative for Unsteady Heat Diffusion

open access: yesFractal and Fractional
In recent decades, the fractional derivative (FD) and memory-dependent derivative (MDD) have been borrowed for modifying the unsteady diffusion process. Yet, according to their definitions, only memory effects in temporal sense are reflected.
Jin-Liang Wang, Hui-Feng Li
doaj   +1 more source

Modulation of Local Environment for Selective Bicarbonate Conversion to Multi‐Carbon Products

open access: yesAdvanced Energy Materials, EarlyView.
Highly porous Cu electrode partially coated with an ionomer/carbon composite enables efficient conversion of bicarbonate to multi‐carbon products. By regulating the local reaction microenvironment, this strategy overcomes selectivity and reaction‐rate limitations, achieving Faradaic efficiencies of 43% for ethylene and 60% for total multi‐carbon ...
Tai Nguyen   +15 more
wiley   +1 more source

Triple flame structure and diffusion flame stabilization [PDF]

open access: yes, 1994
The stabilization of diffusion ñames is studied using asymptotic techniques and numerical tools. The configuration studied corresponda to parallel streams of cold oxidizer and fuel initially separated by a splitter píate.
Poinsot, T.   +5 more
core  

An Intelligent Microfluidics Enabled by Data‐Driven Deep Learning‐Based Microrobot‐Assisted Flow Manipulation

open access: yesAdvanced Intelligent Systems, EarlyView.
An AI‐enabled micromixing framework is developed by integrating cGAN with Bayesian optimization for predictive control of microrobot‐driven flow manipulation. Through this framework, the spatiotemporal evolution of micromixing is learned directly from experimental images, while rapid identification of optimized microrobot actuation strategies is ...
Dineshkumar Loganathan, Chia‐Yuan Chen
wiley   +1 more source

Computation of unsteady flow in turbomachinery [PDF]

open access: yes, 1998
Unsteady flow analysis has been gradually introduced in turbomachinery design systems to improve machine performance and structural integrity. A project on computation of unsteady flows in turbomachinery has been carried out.
Ning, W., Ning, Wei
core  

COX14 Variants Are Associated With Mitochondrial Complex IV Deficiency Nuclear Type 10 (MC4DN10)

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT COX14 encodes a transmembrane protein essential for cytochrome c oxidase (COX) complex assembly. A homozygous missense variant in COX14 was reported in three siblings from a single consanguineous family with severe, fatal infantile mitochondrial complex IV deficiency nuclear type 10 (MC4DN10; MIM# 619053).
Elias K. Awad   +7 more
wiley   +1 more source

Three dimensional frequency-domain solution method for unsteady turbomachinery flows [PDF]

open access: yes, 2003
The three-dimensional calculation of unsteady flows is increasingly gaining importance in the prediction of turbomachinery flow problems. A three-dimensional Euler/Navier-Stokes solver incorporating the time-linearized method and the nonlinear harmonic ...
Vasanthakumar, Parthasarathy
core  

Dye advection without the blur: ML-based flow visualization

open access: yesVisual Informatics
Semi-Lagrangian texture advection (SLTA) enables efficient visualization of 2D and 3D unsteady flow. The major drawback of SLTA-based visualizations is numerical diffusion caused by iterative texture interpolation.
Sebastian Künzel, Daniel Weiskopf
doaj   +1 more source

A Novel Constitutional TUBB Variant Associated With Familial Malformations of Cortical Development

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Most pathogenic tubulin variants arise de novo in sporadic patients, causing severe brain malformations and significant neurodevelopmental impairment. The resulting reproductive disadvantage typically prevents these mutations from being transmitted to offspring.
Elena Cellini   +9 more
wiley   +1 more source

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