Results 111 to 120 of about 3,020,093 (290)

CSTrans: cross-subdomain transformer for unsupervised domain adaptation

Complex & Intelligent Systems
Unsupervised domain adaptation (UDA) aims to make full use of a labeled source domain data to classify an unlabeled target domain data. With the success of Transformer in various vision tasks, existing UDA methods borrow strong Transformer framework to ...
Junchi Liu, Xiang Zhang, Zhigang Luo
doaj   +1 more source

A Pancreatitis‐Inspired Trypsinogen Nanoplatform Reprograms Tumor‐Associated Macrophages via NF‐κB for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
Trypsinogen‐loaded nanoparticles reprogram TAMs via NF‐κB/NLRP3, driving M2→M1 conversion and potent phagocytosis to unleash antitumor immunity. ABSTRACT Although reprogramming tumor‐associated macrophages (TAMs) represents a promising therapeutic strategy, approaches that are both precise and safe remain scarce.
Lei Cao, Yu He, Wenhao Li, Bo Gong, Han Lin, Jianlin Shi, Yuan Yong, Wencheng Wu   +7 more
wiley   +1 more source

Exploring the Role of Depth Information From DAM in Diverse Remote Sensing Semantic Segmentation Tasks

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Existing semantic segmentation methods for remote sensing images focus mainly on planar features to boost performance but inadequately consider the potential advantages of incorporating depth features.
Dehao Zhou, Fukun Bi, Xinghai Hou, Xianping Ma, Zhiliu Yang, Binbin Yang   +5 more
doaj   +1 more source

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

Advanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin, Shicong Zheng, Pei Song, Jie Chang, Zewei Chen, Cang Li, Min Yu, Lude Wang, Shian Yu   +8 more
wiley   +1 more source

Context-Aware Feature Adaptation for Mitigating Negative Transfer in 3D LiDAR Semantic Segmentation

Remote Sensing
Semantic segmentation of 3D LiDAR point clouds is crucial for autonomous driving and urban modeling but requires extensive labeled data. Unsupervised domain adaptation from synthetic to real data offers a promising solution, yet faces the challenge of ...
Lamiae El Mendili, Sylvie Daniel, Thierry Badard   +2 more
doaj   +1 more source

Design and Engineering of an Artificial Bifunctional N‐Deacetylase/N‐Sulfotransferase for the Biosynthesis of N‐Sulfated Heparosan

Advanced Science, EarlyView.
An artificial bifunctional N‐deacetylase/N‐sulfotransferase was engineered in Escherichia coli by combining screened N‐deacetylases with an NST domain. The integrated engineering strategy improved enzyme performance. The optimized enzyme efficiently converted heparosan into N‐sulfated heparosan, addressing a key bottleneck in microbial heparin ...
Xintong Xi, Ruirui Xu, Daoan Wang, Guobin Yin, Xinjing Wang, Haiqin Chen, Guocheng Du, Jian Chen, Zhen Kang   +8 more
wiley   +1 more source

EDIF: boosting unsupervised cross-domain forest fire smoke detection with enhanced domain-invariant features

Geomatics, Natural Hazards & Risk
In forest fire smoke detection tasks, variations in data distribution caused by deployment environments, acquisition devices, and smoke characteristics, along with the scarcity of fire incidents, make it difficult for models to generalize across all ...
Peixian Jin, Xuhong Feng, Pengle Cheng, Mingyu Wang, Xiaodong Liu, Ying Huang   +5 more
doaj   +1 more source

Enhancing Super‐Resolution Spatial Transcriptomics Data by Transfer Learning

Advanced Science, EarlyView.
SpotZoomer employs a transfer‐learning‐based strategy to enhance the resolution of Visium data by leveraging available high‐resolution priors. The resulting super‐resolved maps enable sharper delineation of cell boundaries and more precise inference of cell–cell communication patterns that would otherwise remain obscured at native resolution.
Xiaoyu Li, Lihua Zhang, Wenwen Min
wiley   +1 more source

Unsupervised Domain Adaptation for Instance Segmentation: Extracting Dwellings in Temporary Settlements Across Various Geographical Settings

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Dwelling information is essential for humanitarian emergency response during or in the aftermath of disasters, especially in temporary settlement areas hosting forcibly displaced people.
Getachew Workineh Gella, Charlotte Pelletier, Sebastien Lefevre, Lorenz Wendt, Dirk Tiede, Stefan Lang   +5 more
doaj   +1 more source

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source