Results 61 to 70 of about 387,320 (324)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Local Sensitive Dual Concept Factorization for Unsupervised Feature Selection

open access: yesIEEE Access, 2020
In this paper, we present a novel Local Sensitive Dual Concept Learning (LSDCL) method for the task of unsupervised feature selection. We first reconstruct the original data matrix by the proposed dual concept learning model, which inherits the merit of ...
Hua Zhao   +3 more
doaj   +1 more source

Boosted unsupervised feature selection for tumor gene expression profiles

open access: yesCAAI Transactions on Intelligence Technology
In an unsupervised scenario, it is challenging but essential to eliminate noise and redundant features for tumour gene expression profiles. However, the current unsupervised feature selection methods treat all samples equally, which tend to learn ...
Yifan Shi   +5 more
semanticscholar   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

RMFRASL: Robust Matrix Factorization with Robust Adaptive Structure Learning for Feature Selection

open access: yesAlgorithms, 2022
In this paper, we present a novel unsupervised feature selection method termed robust matrix factorization with robust adaptive structure learning (RMFRASL), which can select discriminative features from a large amount of multimedia data to improve the ...
Shumin Lai   +5 more
doaj   +1 more source

Feature subset selection and ranking for data dimensionality reduction [PDF]

open access: yes, 2005
A new unsupervised forward orthogonal search (FOS) algorithm is introduced for feature selection and ranking. In the new algorithm, features are selected in a stepwise way, one at a time, by estimating the capability of each specified candidate feature ...
Billings, S.A., Wei, H.L.
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Experiments in Clustering Homogeneous XML Documents to Validate an Existing Typology [PDF]

open access: yes, 2005
This paper presents some experiments in clustering homogeneous XMLdocuments to validate an existing classification or more generally anorganisational structure.
Despeyroux, Thierry   +3 more
core   +7 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Unsupervised Minimum Redundancy Maximum Relevance Feature Selection for Predictive Maintenance: Application to a Rotating Machine

open access: yesInternational Journal of Prognostics and Health Management, 2021
Identifying and selecting optimal prognostic health indicators in the context of predictive maintenance is essential to obtain a good model and make accurate predictions.
Valentin Hamaide , François Glineur
doaj   +1 more source

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