Results 131 to 140 of about 246,994 (340)

Methodological factors influencing measurement and processing of plasma reelin in humans [PDF]

open access: yes, 2003
BACKGROUND: Reelin, intensively studied as an extracellular protein that regulates brain development, is also expressed in a variety of tissues and a circulating pool of reelin exists in adult mammals.
Davis, John M   +5 more
core   +3 more sources

Respiratory virus mRNA vaccines: mRNA Design, clinical studies, and future challenges

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Abstract Respiratory infectious diseases frequently erupt on a global scale, with RNA viruses, such as SARS‐CoV‐2, RSV, and influenza viruses, posing challenges to vaccine development due to their high mutation rates. Traditional vaccine development cycles are lengthy and struggle to keep pace with rapidly evolving viruses, whereas messenger RNA (mRNA)
Linlin Zheng, Han Feng
wiley   +1 more source

Minimum free energy predicted base pairing in the 39 nt spliced leader and 5’ UTR of calmodulin mRNA from Trypanosoma cruzi: influence of the multiple trans-splicing sites

open access: yesAnais da Academia Brasileira de Ciências, 2017
We analyzed the compositional changes and the stable base pairs in the predicted secondary structure of the 5’ UTR calmodulin mRNA in T. cruzi. The three copies of calmodulin in T.
FRANKLYN SAMUDIO, ADEILTON BRANDÃO
doaj   +1 more source

An efficient new route to dihydropyranobenzimidazole inhibitors of HCV replication. [PDF]

open access: yes, 2010
A class of dihydropyranobenzimidazole inhibitors was recently discovered that acts against the hepatitis C virus (HCV) in a new way, binding to the IRES-IIa subdomain of the highly conserved 5' untranslated region of the viral RNA and thus preventing the
Bergdahl, B Mikael   +3 more
core   +3 more sources

Apobec-1 complementation factor regulates cell migration and apoptosis through Dickkopf1 by acting on its 3′ untranslated region in MCF7 cells

open access: yesTumor Biology, 2017
A1CF (apobec-1 complementation factor) acts as a component of the apolipoprotein-B messenger RNA editing complex. Previous researches mainly focused on its post-transcriptional cytidine to uridine RNA editing.
Xin Yan   +9 more
doaj   +1 more source

Chromosomal Localization of the Carcinoembryonic Antigen Gene Family and Differential Expression in Various Tumors [PDF]

open access: yes, 1988
Carcinoembryonic antigen (CEA) is a glycoprotein which is important as a tumor marker for a number of human cancers. It is a member of a gene family comprising about 10 closely related genes.
Fiebig, Heinz-Herbert   +8 more
core   +1 more source

Improved ontology for eukaryotic single-exon coding sequences in biological databases [PDF]

open access: yes, 2018
Indexación: Scopus.Efficient extraction of knowledge from biological data requires the development of structured vocabularies to unambiguously define biological terms. This paper proposes descriptions and definitions to disambiguate the term 'single-exon
Clausen, P.   +4 more
core   +2 more sources

Noncoding RNAs in Host–Microbiota Interaction

open access: yesAnimal Research and One Health, EarlyView.
The intricate interplay between gut microbiota and the host exerts a profound impact on host biological processes and disease development. This review highlights the pivotal role of noncoding RNAs (ncRNAs) in this interaction. Host ncRNAs regulate gene expression and microbiota composition, whereas microbial small RNAs (sRNAs) modulate host gene ...
Ziyi Zhao   +7 more
wiley   +1 more source

Conservation of the secondary structure elements of the 5' untranslated region of cardio- and aphthovirus RNAs [PDF]

open access: green, 1989
Evgeny V. Pilipenko   +4 more
openalex   +1 more source

Keratinocyte differentiation-dependent human papillomavirus gene regulation [PDF]

open access: yes, 2017
Human papillomaviruses (HPVs) cause diseases ranging from benign warts to invasive cancers. HPVs infect epithelial cells and their replication cycle is tightly linked with the differentiation process of the infected keratinocyte.
Graham, Sheila V.
core   +1 more source

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