Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment
Advanced Science, EarlyView.Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu +7 more
wiley +1 more source
Prioritization of rs187728237 and rs80320514 as miRNA-related Variants of Human AEG-1 Gene
Medical Laboratory Journal, 2018 Background and objectives: 3chr('39') untranslated region (3chr('39')UTR) single nucleotide polymorphisms (SNPs) represent genetic variations that may potentially affect binding of miRNA to coding genes, potentially leading to complex disorders.
Semira Kheiri +3 more
doaj
Conservation of the secondary structure elements of the 5' untranslated region of cardio- and aphthovirus RNAs [PDF]
, 1989 Evgeny V. Pilipenko +4 more
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Peptide Hormone‐Mediated Regulation of Plant Development and Environmental Adaptability
Advanced Science, EarlyView.In this review, recent advances in understanding the roles of plant peptide hormones in regulating growth, reproduction, and environmental adaptability are systematically summarized. It further elucidates the challenges in studying these peptides, such as their low abundance, functional redundancy, and complex signaling mechanisms, and highlights their
Xin Li +8 more
wiley +1 more source
Corrigendum: Inhibition of SARS-CoV-2 by Targeting Conserved Viral RNA Structures and Sequences
Frontiers in Chemistry, 2022 Shalakha Hegde +3 more
doaj +1 more source
MiR-103a-3p targets the 5\u27 UTR of GPRC5A in pancreatic cells. [PDF]
, 2014 MicroRNAs (miRNAs) are short noncoding RNAs that regulate the expression of their targets in a sequence-dependent manner. For protein-coding transcripts, miRNAs regulate expression levels through binding sites in either the 3\u27 untranslated region (3 ...
Rigoutsos, Isidore, Zhou, Honglei
core +1 more source
Iron regulation of transferrin receptor mRNA levels requires iron-responsive elements and a rapid turnover determinant in the 3′ untranslated region of the mRNA. [PDF]
, 1989 John Casey +4 more
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Advanced Science, EarlyView.This study identifies STAU2 as an oncogenic RNA‐binding protein (RBP) with elevated expression in pancreatic ductal adenocarcinoma (PDAC), where its high levels are significantly correlated with metastatic progression. It elucidates that STAU2 directly binds and regulates PALLD, while mediating the functional role of IQGAP1, thereby driving metastasis ...
Jiayu Ding +16 more
wiley +1 more source
Analyses of the splenic mRNA expressed by rabbits of different immunoglobulin kappa-light chain allotypes: conserved sequences in the 3' untranslated region and allotype-specific probes. [PDF]
, 1983 Andréa Pavirani +5 more
openalex +1 more source
Advanced Science, EarlyView.A personalized nanovaccine combining PLGA‐encapsulated heat‐inactivated CVB3 and membranes from CVB3‐infected breast cancer cells stimulates potent antitumor immunity. It reduces immunosuppressive markers, enhances immune activation, and improves survival in vivo.
Amirhossein Bahreyni +6 more
wiley +1 more source