Results 171 to 180 of about 162,571 (289)

A polymorphism at the microRNA binding site in the 3' untranslated region of RYR3 is associated with outcome in hepatocellular carcinoma

, 2015
Xiaolan Zhang, Zhanjun Guo, Xiaoyan Wu, Chenxing Peng   +3 more
openalex   +2 more sources

PTRF Confers Melanoma‐Acquired Drug Resistance Through the Upregulation of EGFR

Cell Proliferation, EarlyView.
The upregulation of PTRF, a critical caveolar component, and the concomitant increase in caveolae number potentiate cellular proliferation and survival pathways, thereby contributing to melanoma drug resistance. ABSTRACT Melanoma is the most serious type of skin cancer. About half of all melanomas have activating BRAF mutations.
Miao Wang, Ying Cao, Chengcheng Ren, Ke Wang, Yaxiang Wang, Xiaoying Wu, Jian Mao, Qian Liang, Qian Zhang, Hezhe Lu, Xiaowei Xu, Yu‐Sheng Cong   +11 more
wiley   +1 more source

Structural Features of 5' Untranslated Region in Translational Control of Eukaryotes. [PDF]

Int J Mol Sci
Razumova E, Makariuk A, Dontsova O, Shepelev N, Rubtsova M.   +4 more
europepmc   +1 more source

LncRNA H19‐Encoded Micropeptide altH19 Promotes DNA Replication and Mitosis in Myeloma Cells by Enhancing the Phosphorylation of CDK2 at Threonine 160

Cell Proliferation, EarlyView.
The micropeptide altH19 interacts with phosphorylated CDK2 (p‐CDK2), subsequently activating CDK2 phosphorylation. This enhances the downstream E2F1 target gene RB activity, which accelerates DNA replication, ultimately leading to rapid myeloma cell mitosis and proliferation.
Yaxin Zhang, Wenjing Li, Xu Cao, Jiwei Mao, Xiaodan Zhou, Linlin Liu, Ruosi Yao   +6 more
wiley   +1 more source

Molecular identification and phenotypic study of a novel <i>HBB</i>: c.-23A>G mutation in the 5' untranslated region. [PDF]

Front Med (Lausanne)
Shen S, Huang J, Qi H, Liu Z, Zhang W, Yuan X, Zhang Z, Chen H, Xie X, Xiao L, Chen J, Song L.   +11 more
europepmc   +1 more source

An effective live-attenuated Zika vaccine candidate with a modified 5' untranslated region. [PDF]

NPJ Vaccines, 2023
Nazneen F, Thompson EA, Blackwell C, Bai JS, Huang F, Bai F.   +5 more
europepmc   +1 more source

Tristetraprolin Regulates Interleukin-6 Expression Through p38 MAPK-Dependent Affinity Changes with mRNA 3′ Untranslated Region

, 2011
Wenpu Zhao, Min Liu, Nisha J. D’Silva, Keith L. Kirkwood   +3 more
openalex   +2 more sources

Ultra-Deep Sequencing Analysis of the Hepatitis A Virus 5'-Untranslated Region among Cases of the Same Outbreak from a Single Source [PDF]

, 2014
Shuang Wu, Shingo Nakamoto, Tatsuo Kanda, Xia Jiang, Masato Nakamura, Tatsuo Miyamura, Hiroshi Shirasawa, Nobuyuki Sugiura, Azusa Takahashi‐Nakaguchi, Tohru Gonoi, Osamu Yokosuka   +10 more
openalex   +1 more source

Non‐Coding RNAs in Breast Cancer Radioresistance: Mechanisms, Functional Roles and Translational Potentials

Cell Proliferation, EarlyView.
Non‐coding RNAs (ncRNAs) regulate breast cancer radioresistance via cell cycle, DNA repair and tumour microenvironment pathways. Targeting ncRNAs (e.g., HOTAIR and miR‐155) with RNA‐based therapies (ASOs and CRISPR) shows promise but faces delivery challenges.
Xiaohui Zhao, Yuting Qiu, Jie Chen, Danni Wang, Zairui Wang, Shuang Ma, Yimin Liu, Guoying Liu, Zhuofei Bi   +8 more
wiley   +1 more source

Autonomous action and cooperativity between the ONECUT2 transcription factor and its 3' untranslated region. [PDF]

Front Cell Dev Biol, 2023
Steadman K, You S, Srinivas DV, Mouakkad L, Yan Y, Kim M, Venugopal SV, Tanaka H, Freeman MR.   +8 more
europepmc   +1 more source