Results 181 to 190 of about 162,571 (289)

Characterization of the untranslated region of lymphocytic choriomeningitis virus S segment [PDF]

open access: gold, 2019
Satoshi Taniguchi   +15 more
openalex   +1 more source

Alternative Polyadenylation Drives Runaway Pro‐Inflammatory Macrophages in Periodontitis by Enabling Escape From miRNA Repression

open access: yesCell Proliferation, EarlyView.
APA‐Guided Therapeutic miRNA Selection for Periodontitis. ABSTRACT Periodontitis is a chronic inflammatory disease driven by a dysregulated host immune response, in which macrophage‐mediated inflammation shifts from protective to pathological. While monocyte‐derived macrophages (MDMs) are known to adopt a destructive, M1‐like pro‐inflammatory phenotype,
Jing Zhang   +6 more
wiley   +1 more source

Natural recombination of the torque teno canis virus within the ORF1, -2, and -3 genes and the untranslated region. [PDF]

open access: yesVirus Res, 2023
Wang X   +10 more
europepmc   +1 more source

Human FASTK preferentially binds single‐stranded and G‐rich RNA

open access: yesThe FEBS Journal, EarlyView.
Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak   +7 more
wiley   +1 more source

Differential regulation of translational stress responses by herpesvirus ubiquitin deconjugases

open access: yesThe FEBS Journal, EarlyView.
Translating viral mRNAs is challenging due to structural features that may slow translation or induce ribosome stalling. The viral ubiquitin deconjugases encoded by human pathogenic herpesviruses regulate the cellular response to ribosomal stress by inhibiting various branches of the Ribosomal Quality Control (RQC) and activating Ribosomal Stress ...
Jiangnan Liu   +3 more
wiley   +1 more source

Multiple Regulatory Mechanisms Act on the 5′ Untranslated Region of the S-Layer Gene from Thermus thermophilus HB8

open access: green, 2001
Pablo Castán   +6 more
openalex   +1 more source

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