Results 191 to 200 of about 249,320 (341)

SOX10, MITF, and microRNAs: Decoding their interplay in regulating melanoma plasticity

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Recent studies show that the dysregulation of the transcription factor SOX10 is essential for the development and progression of melanoma. MicroRNAs (miRNAs) can regulate the expression of transcription factors at the post‐transcriptional level. The interactions between SOX10 and its targeting miRNAs form network motifs such as feedforward and
Xin Lai   +6 more
wiley   +1 more source

The role of Arbovirus genome untranslated regions on neurotropism [PDF]

open access: yesInternational Journal of Infectious Diseases, 2019
Michael T. Wolfinger   +1 more
openaire   +3 more sources

A promising frontier of circulating messenger RNA in liquid biopsy: From mechanisms to clinical applications

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li   +7 more
wiley   +1 more source

Extrachromosomal Circular DNA: Emerging Insights Into Cardiovascular Disease Mechanisms and Biomarker Potential

open access: yesiLABMED, EarlyView.
Extrachromosomal circular DNA (eccDNA) has quite recently turned out to be a cardinal component in cardiovascular diseases (CVD), governing the gene expression and mechanisms of disease causation. Studies indicated an upregulation of eccDNA in pulmonary arterial hypertension (PAH), which makes it strikingly potential as a sensitive and specific ...
Saim Mahmood Khan   +6 more
wiley   +1 more source

Current Progress in Targeting Human Cytomegalovirus Infection

open access: yesiLABMED, EarlyView.
This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
wiley   +1 more source

Novel polymorphism in the 5′-untranslated region of the interleukin-4 gene [PDF]

open access: bronze, 1999
Akira Takabayashi   +5 more
openalex   +1 more source

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