Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
Systematic identification of disease-causing promoter and untranslated region variants in 8040 undiagnosed individuals with rare disease. [PDF]
Martin-Geary AC +24 more
europepmc +1 more source
microRNA-4717 differentially interacts with its polymorphic target in thePD13′ untranslated region: A mechanism for regulating PD-1 expression and function in HBV-associated liver diseases [PDF]
Guoyu Zhang +9 more
openalex +1 more source
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola +11 more
wiley +1 more source
Translation of HIV-1 unspliced RNA is regulated by 5' untranslated region structure. [PDF]
Cheng Z +9 more
europepmc +1 more source
A motif in the 5'untranslated region of messenger RNAs regulates protein synthesis in a S6 kinase-dependent manner. [PDF]
Shin HC +5 more
europepmc +1 more source
A comprehensive overview of yeast libraries and their role in advancing cell biology
Systematic, genome‐wide yeast mutant libraries have revolutionized systems and cell biology. By allowing high‐throughput interrogation of every gene and protein, they have defined gene essentiality, charted protein localization, illuminated function, mapped interactions, and more.
Din Baruch, Maya Schuldiner, Ofir Klein
wiley +1 more source
Correction to "Dissecting the Conformational Heterogeneity of Stem-Loop Substructures of the Fifth Element in the 5'-Untranslated Region of SARS-CoV-2". [PDF]
Mertinkus KR +7 more
europepmc +1 more source

