Results 211 to 220 of about 246,994 (340)

C/T Polymorphism in the 5′ Untranslated Region of the Apolipoprotein(a) Gene Introduces an Upstream ATG and Reduces In Vitro Translation [PDF]

, 1995
Bernice R. Zysow, Gisela Lindahl, David P. Wade, Brian L. Knight, Richard M. Lawn   +4 more
openalex   +1 more source

Exploring the Therapeutic Potential of MIR‐140‐3p in Osteoarthritis: Targeting CILP and Ferroptosis for Novel Treatment Strategies

Cell Proliferation, EarlyView.
Global landscape. ABSTRACT Osteoarthritis (OA) is a prevalent and debilitating joint disorder that affects millions of individuals worldwide, severely impairing mobility, independence, and quality of life. Emerging evidence suggests that ferroptosis is a critical factor in OA pathogenesis.
Feng Ma, Lexin Wang, Hao Chi, Xinyi Li, Yaoqin Xu, Kexin Chen, Jingfan Zhou, Runqin Yang, Jie Liu, Ke Xu, Xiaoling Yang   +10 more
wiley   +1 more source

An effective live-attenuated Zika vaccine candidate with a modified 5' untranslated region. [PDF]

NPJ Vaccines, 2023
Nazneen F, Thompson EA, Blackwell C, Bai JS, Huang F, Bai F.   +5 more
europepmc   +1 more source

A small deletion in the 3′-untranslated region of the cyclin D1/PRAD1/bcl-1 oncogene in a patient with chronic lymphocytic leukemia [PDF]

, 1998
Yoshitaka Hosokawa, Ritsuro Suzuki, Tatsuroh Joh, Yumiko Maeda, Shigeo Nakamura, Yoshihisa Kodera, Andrew Arnold, Masao Seto   +7 more
openalex   +1 more source

Membraneless Organelles and Phase Separation in Tumours: Mechanisms and Prospects

Cell Proliferation, EarlyView.
The Salient and Novel Findings: This article summarises the latest research advancements in phase separation within tumours, with a particular focus on the role and molecular mechanisms of liquid–liquid phase separation (LLPS) in tumour progression.
Hao Yang, Zhong Chu, Shuwen Han, Yuefen Pan   +3 more
wiley   +1 more source

Identification of a Human VPF/VEGF 3′ Untranslated Region Mediating Hypoxia-induced mRNA Stability [PDF]

, 1998
Kevin P. Claffey, Shu‐Ching Shih, Andrew R. Mullen, Suzan Dziennis, Jennifer L. Cusick, Kristin Abrams, Sam W. Lee, Michael Detmar   +7 more
openalex   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

Systematic identification of disease-causing promoter and untranslated region variants in 8040 undiagnosed individuals with rare disease. [PDF]

Genome Med
Martin-Geary AC, Blakes AJM, Dawes R, Findlay SD, Lord J, Dong S, Walker S, Talbot-Martin J, Wieder N, D'Souza EN, Fernandes M, Hilton S, Lahiri N, Campbell C, Jenkinson S, DeGoede CGEL, Anderson ER, Candler T, Firth H, Burge CB, Sanders SJ, Ellingford J, Baralle D, Banka S, Whiffin N.   +24 more
europepmc   +1 more source

A Functional Single Nucleotide Polymorphism in the 3' Untranslated Region of the Porcine JARID2 Gene Is Associated with Aggressive Behavior of Weaned Pigs after Mixing. [PDF]

Int J Mol Sci, 2023
Yang H, Zhang C, Chao X, Zhao J, Liu M, Chen J, Liu S, Wang T, Muhammad A, Schinckel AP, Zhou B.   +10 more
europepmc   +1 more source

Mutations Altering the Predicted Secondary Structure of a Chloroplast 5′ Untranslated Region Affect Its Physical and Biochemical Properties as Well as Its Ability To Promote Translation of Reporter mRNAs Both in the Chlamydomonas reinhardtii Chloroplast and in Escherichia coli

, 1999
David C. Fargo, John E. Boynton, Nicholas W. Gillham   +2 more
openalex   +1 more source